112933-66-1

Upstream product

• 75-15-0 carbon disulfide 
• 39594-84-8 4-methylphenyl chlorothioformate 
• 106-45-6 para-thiocresol 
• 18241-63-9 p-methylphenyl thiolmethylacetate 

Downstream Products

• 106-45-6 para-thiocresol 
• 63418-53-1 N-benzylpropionthioamide 

Relevant academic research and scientific papers

Kinetics and mechanism of the aminolysis of aryl propanedithioates in acetonitrile

The kinetics and mechanism of the aminolysis of aryl proanedithioates with benzylamines are investigated in acetonitrile at - 35.0 °C. A large magnitude of the Hammett (ρx and ρz) and Broensted (βx and βz) coefficients and exceptionally large cross-interaction constant ρxz(= 3.5) are consistent with a stepwise mechanism in which leaving group expulsion from an intermediate, T±, is the rate-determining step. The faster rates observed for dithio esters (I1) than for thio esters (I), and the validity of the reactivity-selectivity principle (RSP) are also in line with the mechanism proposed. The kH/kD values (= 1.0-1.8) determined with deuterated benzylamines (XC6H4CH2ND2) and the activation parameters, ΔH≠(?8 kcal mol-1) and ΔS≠(= -16 to -23 e.u.), suggest that proton transfer occurs concurrently with leaving group departure in the transition state.

A New Rapid Synthesis of Phenyl Dithiocarboxylates

The otherwise difficultly accessible phenyl dithiocarboxylates are prepared in good yields by the reaction of S-phenyl carbonochloridothioate with halomagnesium or sodium dithiocarboxylates.