39594-84-8

Upstream product

• 75-44-5 phosgene 
• 106-45-6 para-thiocresol 
• 3274-12-2 4-methyl-4-(trichloromethyl)cyclohexa-2,5-dien-1-one 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 106-44-5 p-cresol 
• 75-70-7 trichloromethyl mercaptan 

Downstream Products

• 26012-09-9 Thiocarbonic acid O-[5-chloro-2-(2,4-dichloro-phenoxy)-phenyl] ester S-p-tolyl ester 
• 85975-90-2 (p-Tolylthio)carbonyl-isothiocyanat 
• 66018-75-5 phenyl-thiocarbamic acid S-4-methylphenyl ester 
• 51955-56-7 S-p-tolyl benzylcarbamothioate 
• 85975-87-7 N,3-Diisopropyl-N'-<(p-tolylthio)carbonyl>-1,3-thiazetidin-2,4-diimin 
• 85975-78-6 3-Cyclohexyl-4-phenyl-N-<(p-tolylthio)carbonyl>-1,3-thiazetidin-2-imin 
• 85992-13-8 3,4,5,6-Tetrahydro-3,5-dimethyl-4,6-diphenyl-N-<(p-tolylthio)carbonyl>-2H-1,3,5-thiadiazin-2-imin 
• 1440419-50-0 S-phenyl [(7-(hex-5-en-1-yl)-1,4-dioxaspiro[4.5]dec-8-en-7-yl)methyl](4-methoxybenzyl)carbamothioate 

Relevant academic research and scientific papers

Specific Fluorescent Probe Based on "protect-Deprotect" to Visualize the Norepinephrine Signaling Pathway and Drug Intervention Tracers

In recent years, increased social pressure and other factors have led to a surge in the number of people suffering from depression: studies show that quite a few people will experience major depression in their lifetime. Currently, it is widely believed t

Fluorescein derivative DCCT and preparation method and application thereof

The invention provides a fluorescein derivative DCCT and a preparation method and application thereof. The Chinese name of the fluorescein derivative is O,O'-(2',7'-dichlorofluorescein-3',6'- diyl)S,S'-di-p-tolyl bis(carbonate), which is abbreviated as DC

Bis-Acetyl Carbazole: A Photoremovable Protecting Group for Sequential Release of Two Different Functional Groups and Its Application in Therapeutic Release

In this paper, we present fluorescent photoremovable protecting groups (FPRPG) based on bis-acetyl carbazole for the release of two different functional groups such as carboxylic acids, alcohols, thiols, and amines in a sequential fashion. Dual-arm caged bis-acetyl carbazoles with different combinations of two unlike functional groups were synthesized. Photophysical studies showed that caged bis-acetyl carbazoles are blue fluorescent and their emission properties are sensitive to the environment. Sequential photorelease of two different functional groups by bis-acetyl carbazole was analyzed by HPLC, UV and emission spectroscopy. The mechanism of the dual release by bis-acetyl carbazole was investigated and supported by TD-DFT calculations. To demonstrate the applicability of the dual release ability of bis-acetyl carbazole FPRPG, we synthesized a drug delivery system (DDS) in which one arm of bis-acetyl carbazole is linked to the carboxylic functional group of chlorambucil (CBL) and the other arm is attached to the hydroxyl group of ferulic acid ethyl ester (FAEE). In vitro studies showed that our DDS presents excellent properties such as photoregulated dual drug delivery, cellular uptake, and biocompatibility.

Process for producing phenyl chlorothioformates

Phenyl chlorothioformates are produced in high yields easily and safely by (1) allowing sulfur dioxide to react with a mixed solution consisting of perchloromethyl mercaptan, an organic solvent and water, (2) removing the aqueous layer from the reaction m