112936-15-9Relevant academic research and scientific papers
Towards Tumor Targeting with Copper-radiolabelled Macrocycle-Antibody Conjugates: Synthesis, Antibody Linkage, and Complexation Behaviour
Morphy, J. Richard,Parker, David,Kataky, Ritu,Eaton, Michael A. W.,Millican, Andrew T.,et al.
, p. 573 - 585 (2007/10/02)
A set of four tetra-azamacrocyclic ligands bearing aminomethylphenyl substituents have been prepared and may be attached to a monoclonal antibody via an intermediate thiol-specific vinylpyridine linker molecule.The resultant conjugates may be efficiently
Antibody Labelling with Functionalised Cyclam Macrocycles
Morphy, J. Richard,Parker, David,Alexander, Rikki,Bains, Amarjit,Carne, Alex F.,et al.
, p. 156 - 158 (2007/10/02)
Functionalised 'cyclam' macrocyclic ligands have been selectively attached to thiol residues on a monoclonal antibody and form kinetically inert complexes with Cu2+ and TcV.
