1129403-56-0 Usage
General Description
BBI-503, also known as BB-503, is a small molecule inhibitor that targets cancer stem cells. It works by inhibiting the STAT3 signaling pathway, which is known to play a critical role in the self-renewal and survival of cancer stem cells. By targeting these cells, BBI-503 has the potential to prevent tumor growth and recurrence. In preclinical studies, BBI-503 has shown promising anti-cancer activity against a variety of solid tumors, including breast, lung, and colon cancer. It is currently being investigated in clinical trials for the treatment of advanced solid tumors, either as a standalone therapy or in combination with other anti-cancer agents.
Check Digit Verification of cas no
The CAS Registry Mumber 1129403-56-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,9,4,0 and 3 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1129403-56:
(9*1)+(8*1)+(7*2)+(6*9)+(5*4)+(4*0)+(3*3)+(2*5)+(1*6)=130
130 % 10 = 0
So 1129403-56-0 is a valid CAS Registry Number.
1129403-56-0Relevant articles and documents
Treatment of obesity
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Paragraph 0441-0444, (2021/07/06)
The invention provides novel methods of treating or preventing obesity or overweight and closely associated comorbidities therewith in a mammalian subject including human.
HETEROCYCLIC SUBSTITUTED-3-HETEROARYLIDENYL-2-INDOLINONE DERIVATIVE
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Paragraph 0390; 0391; 0392; 0393, (2014/09/30)
Disclosed is a compound represented by formula (1) or a pharmacologically acceptable salt thereof. (In the formula, R1 is optionally substituted heteroaryl etc.; R2 is hydrogen etc.; R3 and R4 are each independently hydrogen etc., R5 is the following group: (wherein Y is optionally substituted five membered heteroaryl etc., R9a is optionally substituted aryl etc., R9b and R9c are each dependently hydrogen etc., and m is the integral 0 etc.) etc.; R6 is hydrogen etc.; and R7 is hydrogen etc.
