113010-10-9Relevant academic research and scientific papers
An Alternative Total Synthesis of Rutaecarpine and Vasicolinone Alkaloids
Koekoesi, Jozsef,Szasz, Gyoergy,Hermecz, Istvan
, p. 2995 - 2998 (2007/10/02)
Rutaecarpine (6) and vasicolinone (9) alkaloids were alternatively prepared by Fischer indolization of 3-(phenylhydrazonomethyl)pyrroloquinazolinone (4) under thermal and acidic conditions, respectively.
Total Syntheses of Vasicoline and Vasicolinone
Nakagawa, Yumi,Stevens, Robert V.
, p. 1873 - 1876 (2007/10/02)
Bis-ortho-nitration of α-phenyl-N-(phenylmethyl)-γ-butanelactam (6) using acetyl nitrate followed by reduction and regiospecific dehydrative cyclization afforded quinazoline 12.The aniline moiety in 12 could be dimethylated by using aqueous formaldehyde a
A SHORT SYNTHESIS OF RUTECARPINE AND/OR VASICOLINONE FROM 2-CHLORO-3-(INDOL-3-YL)ETHYLQUINAZOLIN-4(3H)-ONE: EVIDENCE FOR THE PARTICIPATION OF THE SPIRO INTERMEDIATE
Kaneko, Chikara,Chiba, Takuo,Kasai, Kouichi,Miwa, Chiemi
, p. 1385 - 1390 (2007/10/02)
A new route to rutecarpine and/or vasicolinone from 2-chloro-4-quinazolone through an acid catalyzed cyclization of 2-chloro-3-indolylethylquinazolin-4-one has been developed and the mechanism of the cyclization reaction clarified.
