1131-09-5 Usage
Uses
Used in Chemical Research:
BENZO[B]THIOPHENE-3-ACETIC ACID is used as a core structure for the synthesis of complex chemical compounds, facilitating the development of new materials and pharmaceuticals. Its unique fusion of benzene, thiophene, and acetic acid functional groups provides a versatile platform for chemical reactions and modifications.
Used in Biochemical Research:
In the field of biochemistry, BENZO[B]THIOPHENE-3-ACETIC ACID is utilized for studying the interactions between various biomolecules and its potential applications in drug discovery. Its specific properties and reactivity allow researchers to explore its binding affinity and selectivity towards biological targets, contributing to the advancement of novel therapeutic agents.
Used in Pharmaceutical Development:
BENZO[B]THIOPHENE-3-ACETIC ACID is employed as a building block in the design and synthesis of pharmaceutical compounds. Its unique structure and functional groups enable the development of new drugs with improved pharmacological properties, such as enhanced potency, selectivity, and reduced side effects.
Used in Material Science:
In material science, BENZO[B]THIOPHENE-3-ACETIC ACID is utilized for the development of novel materials with specific properties, such as conductivity, stability, and responsiveness to external stimuli. Its incorporation into polymers, nanoparticles, or other composite materials can lead to the creation of advanced materials for various applications, including sensors, energy storage, and electronic devices.
Overall, BENZO[B]THIOPHENE-3-ACETIC ACID is a valuable chemical compound with diverse applications across multiple industries, including chemical research, biochemistry, pharmaceutical development, and material science. Its unique structure and functional groups make it an essential component in the synthesis of complex compounds and the development of innovative materials and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 1131-09-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,3 and 1 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1131-09:
(6*1)+(5*1)+(4*3)+(3*1)+(2*0)+(1*9)=35
35 % 10 = 5
So 1131-09-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H8O2S/c11-10(12)5-7-6-13-9-4-2-1-3-8(7)9/h1-4,6H,5H2,(H,11,12)
1131-09-5Relevant academic research and scientific papers
Pd(OH)2/C, a Practical and Efficient Catalyst for the Carboxylation of Benzylic Bromides with Carbon Monoxide
Wakuluk-Machado, Anne-Marie,Dewez, Damien F.,Baguia, Hajar,Imbratta, Miguel,Echeverria, Pierre-Georges,Evano, Gwilherm
, p. 713 - 723 (2020/02/04)
A simple, efficient, cheap, and broadly applicable system for the carboxylation of benzylic bromides with carbon monoxide and water is reported. Upon simple reaction with only 2.5 wt % of Pearlman's catalyst and 10 mol % of tetrabutylammonium bromide in tetrahydrofuran at 110 °C for 4 h, a range of benzylic bromides can be smoothly converted to the corresponding arylacetic acids in good to excellent yields after simple extraction and acid-base wash. The reaction was found to be broadly applicable, scalable, and could be successfully extended to the use of ex situ-generated carbon monoxide and applied to the synthesis of the nonsteroidal anti-inflammatory drug diclofenac.
Ruthenium-catalyzed umpolung carboxylation of hydrazones with CO2
Yan, Si-Shun,Zhu, Lei,Ye, Jian-Heng,Zhang, Zhen,Huang, He,Zeng, Huiying,Li, Chao-Jun,Lan, Yu,Yu, Da-Gang
, p. 4873 - 4878 (2018/06/07)
The first ruthenium-catalyzed umpolung carboxylation of hydrazones with CO2 to generate important aryl acetic acids is reported. Besides aldehyde hydrazones, a variety of ketone hydrazones, which have not been successfully applied in previous umpolung reactions with other reactive electrophiles, also show high reactivity and selectivity under mild conditions. Moreover, this operationally simple protocol features good functional group tolerance, is readily scalable, and offers easy derivation of important structures, including bioactive felbinac and adiphenine. Computational studies reveal that this umpolung reaction proceeds through the generation of a Ru-nitrenoid followed by concerted [4 + 2] cycloaddition with CO2.
