1131737-05-7 Usage
Description
(R)-1-(2,6-dichlorophenyl)ethanamine hydrochloride, also known as [R]-(-)-norephedrine hydrochloride, is a phenethylamine chemical compound derived from amphetamine. It functions as a selective alpha-1 adrenergic receptor agonist, stimulating specific receptors in the sympathetic nervous system to induce vasoconstriction in blood vessels. (R)-1-(2,6-dichlorophenyl)ethanamine hydrochloride is utilized in various pharmaceutical and research applications.
Uses
Used in Pharmaceutical Industry:
(R)-1-(2,6-dichlorophenyl)ethanamine hydrochloride is used as a decongestant for its ability to constrict blood vessels, reducing swelling and congestion, particularly in conditions such as nasal congestion.
Used in Weight Management Applications:
In the health and wellness industry, (R)-1-(2,6-dichlorophenyl)ethanamine hydrochloride serves as an appetite suppressant, helping to manage weight by reducing the desire to eat.
Used in Chemical Synthesis:
(R)-1-(2,6-dichlorophenyl)ethanamine hydrochloride is utilized as a key intermediate in the synthesis of certain pharmaceuticals and research chemicals, contributing to the development of new medications and compounds for various therapeutic purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 1131737-05-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,1,7,3 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1131737-05:
(9*1)+(8*1)+(7*3)+(6*1)+(5*7)+(4*3)+(3*7)+(2*0)+(1*5)=117
117 % 10 = 7
So 1131737-05-7 is a valid CAS Registry Number.
1131737-05-7Relevant articles and documents
1-(2,6-Dichlorophenyl)ethylamine: A new and efficient chiral auxiliary for the Staudinger β-lactam synthesis
Hashimoto, Yukihiko,Kai, Akiyoshi,Saigo, Kazuhiko
, p. 8821 - 8824 (1995)
The diastereoselective synthesis of β-lactams by the Staudinger reaction was examined using chiral imines, derived from substituted 1-phenylethylamines. Among them, 1-(2,6-dichlorophenyl)ethylamine was found to be a new and efficient chiral auxiliary, and the corresponding cis-β-lactams were obtained in good to excellent yields with high diastereoselectivity.
Native Amine-Directed ortho -C-H Halogenation and Acetoxylation /Condensation of Benzylamines
Chand-Thakuri, Pratibha,Alahakoon, Indunil,Liu, Daniel,Kapoor, Mohit,Kennedy, John F.,Jenkins, Kenneth W.,Rabon, Allison M.,Young, Michael C.
, p. 341 - 354 (2021/10/07)
Free or unfunctionalized benzylamines are well known to participate in C-H activation in the presence of palladium salts. Despite the ease with which these complexes can be activated, subsequent functionalization of the dimeric cyclometalates can be chall
Stereoselective Nucleophilic Additions to the Carbon-Nitrogen Double Bond. 2. Chiral Iminium Ions Derived from "Second Generation" Chiral Amines
Polniaszek, Richard P.,Kaufman, Craig R.
, p. 4859 - 4863 (2007/10/02)
"Second generation" chiral amines (1S)-(-)-1-(2-chlorophenyl)ethylamine (4) and (1S)-(-)-1-(2,6-dichlorophenyl)ethylamine (5) have been prepared from commercially available (S)-(-)-α-phenethylamine.These chiral reagents have been incorporated into chiral
