53066-19-6

Basic information

• Product Name: 1-(2,6-DICHLOROPHENYL)ETHANOL
• Synonyms: 2,6-DICHLOROPHENYLMETHYL CARBINOL;1-(2,6-DICHLOROPHENYL)ETHANOL;2,6-Dichloro-alpha-methylbenzyl alcohol~2,6-Dichlorophenyl methyl carbinol;2,6-dichloro-alpha-methylbenzyl alcohol;2,6-dichloro-à-methylbenzyl alcohol;2,6-Dichloro-α-methylbenzenemethanol;α-Methyl-2,6-dichlorobenzenemethanol;2,6-Dichloro-alpha-methylbenzenemethanol
• CAS NO: 53066-19-6
• Molecular Formula: C₈H₈Cl₂O
• Molecular Weight: 191.05
• EINECS: 258-340-2
• Product Categories: Benzhydrols, Benzyl & Special Alcohols
• Mol File: 53066-19-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: 34-35℃
• Boiling Point: 117-118°C 4mm
• Flash Point: 117-118°C/4mm
• Appearance: /
• Density: 1.323
• Vapor Pressure: 0.00569mmHg at 25°C
• Refractive Index: 1.5670
• Storage Temp.: 2-8°C
• BRN: 3243202
• CAS DataBase Reference: 1-(2,6-DICHLOROPHENYL)ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,6-DICHLOROPHENYL)ETHANOL(53066-19-6)
• EPA Substance Registry System: 1-(2,6-DICHLOROPHENYL)ETHANOL(53066-19-6)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 53066-19-6(Hazardous Substances Data)

Usage

General Description

1-(2,6-dichlorophenyl)ethanol is a chemical compound with a molecular formula C8H8Cl2O. It is a white crystalline solid with a slight phenolic odor. 1-(2,6-dichlorophenyl)ethanol is often used as a preservative and antimicrobial agent in various industries, including cosmetics, pharmaceuticals, and personal care products. It is also used as a precursor in the synthesis of other chemicals. 1-(2,6-dichlorophenyl)ethanol is known for its antimicrobial and anti-fungal properties, and it is effective against a wide range of microorganisms. However, it is important to handle this compound with care, as it may cause irritation to the skin and eyes and should be used in a well-ventilated area.

InChI:InChI=1/C8H8Cl2O/c1-5(11)8-6(9)3-2-4-7(8)10/h2-5,11H,1H3

Upstream product

• 917-64-6 methyl magnesium iodide 
• 83-38-5 2,6-dichlorobenzaldehyde 
• 75-16-1 methylmagnesium bromide 
• 75-24-1 trimethylaluminum 
• 2040-05-3 2,6 dichloroacetophenone 

Downstream Products

• 2040-05-3 2,6 dichloroacetophenone 
• 1195962-61-8 (1E)-2-methyl-1-(1-(2,6-dichlorophenyl)ethoxy)-pent-1-en-3-one 
• 1613148-62-1 3-(1-(2,6-dichlorophenyl)ethoxy)-2-nitropyridine 

Relevant articles and documents

ATF6 MODULATORS AND USES THEREOF

Compounds (I) as modulators of Activating Transcription Factor 6 (ATF6) are provided. The compounds may find use as therapeutic agents for the treatment of diseases or disorders mediated by ATF6 and may find particular use in the treatment of viral infections, neurodegenerative diseases, vascular diseases, or cancer.

Versatile Catalytic Hydrogenation Using A Simple Tin(IV) Lewis Acid

Despite the rapid development of frustrated Lewis pair (FLP) chemistry over the last ten years, its application in catalytic hydrogenations remains dependent on a narrow family of structurally similar early main-group Lewis acids (LAs), inevitably placing limitations on reactivity, sensitivity and substrate scope. Herein we describe the FLP-mediated H2activation and catalytic hydrogenation activity of the alternative LA iPr3SnOTf, which acts as a surrogate for the trialkylstannylium ion iPr3Sn+, and is rapidly and easily prepared from simple, inexpensive starting materials. This highly thermally robust LA is found to be competent in the hydrogenation of a number of different unsaturated functional groups (which is unique to date for main-group FLP LAs not based on boron), and also displays a remarkable tolerance to moisture.

Friedel-crafts reaction of benzyl fluorides: Selective activation of C-f bonds as enabled by hydrogen bonding

A Friedel-Crafts benzylation of arenes with benzyl fluorides has been developed. The reaction produces 1,1-diaryl alkanes in good yield under mild conditions without the need for a transition metal or a strong Lewis acid. A mechanism involving activation of the C-F bond through hydrogen bonding is proposed. This mode of activation enables the selective reaction of benzylic C-F bonds in the presence of other benzylic leaving groups.