113193-64-9Relevant academic research and scientific papers
Synthesis and pharmacological evaluation of 3-aryl-3-azolylpropan-1-amines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors
Lee, Ki-Ho,Park, Chun-Eung,Min, Kyung-Hyun,Shin, Yong-Je,Chung, Coo-Min,Kim, Hui-Ho,Yoon, Hae-Jeoung,Won-Kim,Ryu, Eun-Ju,Shin, Yu-Jin,Nam, Hyun-Sik,Cho, Jeong-Woo,Lee, Hee-Yoon
scheme or table, p. 5567 - 5571 (2010/12/29)
A series of 3-aryl-3-azolylpropan-1-amines was prepared and screened for its capability of inhibiting monoamine reuptake. Analogs with nanomolar potency, good human in vitro microsomal stability, and low drug-drug interaction potential were described. In
A CONVENIENT SYNTHESIS OF 1H-1,2,4-TRIAZOL-1-YL-PROPAN-3-ONE DERIVATIVES BY MODIFIED MANNICH REACTION
Takahashi, Kimio,Shimizu, Sumio,Ogata, Masaru
, p. 809 - 816 (2007/10/02)
1H-1,2,4-Triazol-yl-propan-3-ones were synthesized regioselectively using a modified Mannich reaction.Reactions of enones and Mannich bases with imidazole are also described.
