113240-61-2Relevant articles and documents
Novel boronate esters
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Page/Page column 11, (2008/06/13)
The present invention relates to optically active boronate derivatives which are useful as intermediates for the synthesis of HMG-CoA enzyme inhibitors such as atorvastatin, cerivastatin, rosuvastatin, pitavastatin, and fluvastatin.
A Highly Stereoselective Route to the Four Stereoisomers of a Six-Carbon Synthon
Prasad, Kapa,Chen, Kau-Ming,Repic, Oljan,Hardtmann, Goetz E.
, p. 307 - 310 (2007/10/02)
The syntheses of chiral synthones 13-16 are described utilizing the chiral pool approach starting from either S- or R-malic acid.
Imidazole analogs of mevalonolactone and derivatives thereof for use in inhibiting cholesterol biosynthesis and lowering blood cholesterol level
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, (2008/06/13)
Compounds of the formula STR1 and the pharmaceutically acceptable acid addition salts thereof, wherein the various substituents are defined hereinbelow and the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level and, therefore, in the treatment of hyperlipoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.