113247-71-5

Basic information

• Product Name: N-benzyloxycarbonyl-O-benzyl-L-tyrosyl-2,L-Ser⁵-O-(11,33-tetraisopropyldisiloxane-1,3-diyl)-L-serylglycyl-L-phenylalanyl-L-serine> benzyl ester
• Synonyms: N-benzyloxycarbonyl-O-benzyl-L-tyrosyl-2,L-Ser⁵-O-(11,33-tetraisopropyldisiloxane-1,3-diyl)-L-serylglycyl-L-phenylalanyl-L-serine> benzyl ester
• CAS NO: 113247-71-5
• Molecular Weight: 1116.47
• Mol File: 113247-71-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyloxycarbonyl-O-benzyl-L-tyrosyl-2,L-Ser⁵-O-(11,33-tetraisopropyldisiloxane-1,3-diyl)-L-serylglycyl-L-phenylalanyl-L-serine> benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyloxycarbonyl-O-benzyl-L-tyrosyl-2,L-Ser⁵-O-(11,33-tetraisopropyldisiloxane-1,3-diyl)-L-serylglycyl-L-phenylalanyl-L-serine> benzyl ester(113247-71-5)
• EPA Substance Registry System: N-benzyloxycarbonyl-O-benzyl-L-tyrosyl-2,L-Ser⁵-O-(11,33-tetraisopropyldisiloxane-1,3-diyl)-L-serylglycyl-L-phenylalanyl-L-serine> benzyl ester(113247-71-5)

Safety Data

• Hazardous Substances Data: 113247-71-5(Hazardous Substances Data)

Upstream product

• 113266-07-2 N-fluorenylmethoxycarbonyl-O-t-butyl-L-seryl-glycin 
• 113266-08-3 O-t-butyl-L-seryl-glycyl-L-phenylalanyl-O-t-butyl-L-serine benzyl ester 
• 113247-73-7 N-fluorenylmethoxycarbonyl-O-t-butyl-L-serylglycyne benzyl ester 
• 81672-17-5 N-fluorenylmethoxycarbonyl-O-t-butyl-L-serylglycyne 
• 113247-69-1 N-benzyloxycarbonyl-O-benzyl-L-tyrosyl-O-t-butyl-L-serylglycyl-L-phenylalanyl-O-t-butyl-L-serine benzyl ester 
• 113247-68-0 N-fluorenylmethoxycarbonyl-O-t-butyl-L-seryl-glycyl-L-phenylalanyl-O-t-butyl-L-serine benzyl ester 
• 113266-06-1 N-fluorenylmethoxycarbonyl-O-t-butyl-L-seryl-glycin benzyl ester 
• 113247-74-8 N-fluorenylmethoxycarbonyl-L-phenylalanine-O-t-butyl-L-serine benzyl ester 
• 126814-53-7 (S)-2-Benzyloxycarbonylamino-3-(4-benzyloxy-phenyl)-propionic acid benzotriazol-1-yl ester 
• 73724-47-7 N-fluorenylmethoxycarbonyl-O-t-butyl serine benzyl ester 
• 113247-78-2 L-phenylalanine-O-t-butyl-L-serine benzyl ester 
• 113247-75-9 O-t-butyl serine benzyl ester 
• 127633-31-2 Fmoc-Phe-benzotriazolyl ester 
• 35661-40-6 N-Fmoc L-Phe 

Downstream Products

• 113247-65-7 L-tyrosyl2,L-Ser⁵-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-L-serylglycyl-L-phenylalanyl-L-serine> 

Relevant articles and documents

Studies on Conformationally Restricted, Disiloxane Bridged Analogues of the Enkephalins

Solution-phase synthesis of protected 2, Ser5>- and 2, Ser5>-enkephalins, followed by treatment with 1,3-dichloro-1,1,3,3-tetraisopropyldisiloxane i2Si(Cl)-O-Si(Cl)Pri2> in base have yielded cyclic bridged disiloxane analogues showing biological activity in an in vitro assay.Highfield (1)H n.m.r. studies augmented by n.O.e. difference spectroscopy, temperature dependence studies of the amide protons, and the use of computer graphics support the presence of a 2-->5 H-bonded β-bend conformation for the most biologically potent of the cyclic analogues.