1132667-73-2Relevant academic research and scientific papers
Construction of thiazines and oxathianes: Via [3 + 3] annulation of N -tosylaziridinedicarboxylates and oxiranes with 1,4-dithiane-2,5-diol: Application towards the synthesis of bioactive molecules
Varshnaya, Rohit Kumar,Banerjee, Prabal
, p. 5182 - 5190 (2017/07/10)
Lewis acid catalyzed [3 + 3] annulation of N-tosylaziridinedicarboxylates and oxiranes with in situ generated mercaptoaldehyde for the synthesis of functionalized thiazine and oxathiane derivatives has been developed. Additionally, this method facilitates the derivatization of thiazines by detosylation and Krapcho monodecarboxylation.
Direct aza-darzens aziridination of N-tosylimines with 2-bromomalonates for the synthesis of highly functionalized donor-acceptor aziridines
Wu, Xingxing,Li, Lei,Zhang, Junliang
, p. 3485 - 3489 (2013/02/22)
An approach to highly functionalized donor-acceptor aziridines by the aziridination of N-tosylimines and 2-bromomalonates in the presence of sodium hydride under mild conditions has been developed. The high-yielding reaction has a relatively broad scope and can be easily scaled up to the gram level.
Facile iodine(III)-induced oxidative cycloaddition of N-sulfonyl imines with methylene compounds under neutral conditions
Fan, Renhua,Wang, Linfei,Ye, Yang,Zhang, Jin
experimental part, p. 3857 - 3859 (2009/10/11)
An efficient oxidative cycloaddition of N-sulfonyl imines with methylene compounds using PhIO with a catalytic amount of KI under neutral conditions, which affords 2,2-difunctionalized aziridines in good to excellent yields, is reported.
Iodobenzene diacetate/tetrabutylammonium iodide-induced aziridination of N-tosylimines with activated methylene compounds under mild conditions
Fan, Renhua,Ye, Yang
supporting information; scheme or table, p. 1526 - 1530 (2009/07/01)
Aziridination of N-tosylimines with activated methylene compounds induced by iodobenzene diacetate [PhI(OAc)2] and tetrabutylammonium bromide [Bu4NBr] afforded the corresponding 2,2-difunctionalized aziridines in good yields with the aid of a catalytic amount of base. The reaction is hypothesized to proceed via a tandem nucleophilic addition-oxidative cyclization pathway.
