1132667-73-2

Basic information

• Product Name: diethyl 3-(4-cyanophenyl)-1-tosylaziridine-2,2-dicarboxylate
• Synonyms: diethyl 3-(4-cyanophenyl)-1-tosylaziridine-2,2-dicarboxylate
• CAS NO: 1132667-73-2
• Molecular Weight: 442.492
• Mol File: 1132667-73-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: diethyl 3-(4-cyanophenyl)-1-tosylaziridine-2,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 3-(4-cyanophenyl)-1-tosylaziridine-2,2-dicarboxylate(1132667-73-2)
• EPA Substance Registry System: diethyl 3-(4-cyanophenyl)-1-tosylaziridine-2,2-dicarboxylate(1132667-73-2)

Safety Data

• Hazardous Substances Data: 1132667-73-2(Hazardous Substances Data)

Upstream product

• 685-87-0 Diethyl 2-bromomalonate 
• 143206-01-3 N-(4-cyanobenzylidene)-p-toluenesulfonamide 
• 105-53-3 diethyl malonate 

Downstream Products

• 1342891-89-7 diethyl 5-(4-cyanophenyl)-3-(4-methoxyphenyl)-1-tosyl-1H-pyrrole-2,2(5H)-dicarboxylate 

Relevant articles and documents

Construction of thiazines and oxathianes: Via [3 + 3] annulation of N -tosylaziridinedicarboxylates and oxiranes with 1,4-dithiane-2,5-diol: Application towards the synthesis of bioactive molecules

Lewis acid catalyzed [3 + 3] annulation of N-tosylaziridinedicarboxylates and oxiranes with in situ generated mercaptoaldehyde for the synthesis of functionalized thiazine and oxathiane derivatives has been developed. Additionally, this method facilitates the derivatization of thiazines by detosylation and Krapcho monodecarboxylation.

Facile iodine(III)-induced oxidative cycloaddition of N-sulfonyl imines with methylene compounds under neutral conditions

An efficient oxidative cycloaddition of N-sulfonyl imines with methylene compounds using PhIO with a catalytic amount of KI under neutral conditions, which affords 2,2-difunctionalized aziridines in good to excellent yields, is reported.