113273-81-7

Basic information

• Product Name: (2S,4R,5R)-2-Isopropyl-4-methyl-5-phenyl-pyrrolidine-2,4-dicarboxylic acid dimethyl ester
• Synonyms: (2S,4R,5R)-2-Isopropyl-4-methyl-5-phenyl-pyrrolidine-2,4-dicarboxylic acid dimethyl ester
• CAS NO: 113273-81-7
• Molecular Weight: 319.401
• Mol File: 113273-81-7.mol

Chemical Properties

• CAS DataBase Reference: (2S,4R,5R)-2-Isopropyl-4-methyl-5-phenyl-pyrrolidine-2,4-dicarboxylic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R,5R)-2-Isopropyl-4-methyl-5-phenyl-pyrrolidine-2,4-dicarboxylic acid dimethyl ester(113273-81-7)
• EPA Substance Registry System: (2S,4R,5R)-2-Isopropyl-4-methyl-5-phenyl-pyrrolidine-2,4-dicarboxylic acid dimethyl ester(113273-81-7)

Safety Data

• Hazardous Substances Data: 113273-81-7(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 13803-83-3 methyl 2-(benzylideneamino)-3-methylbutanoate 
• 80-62-6 methacrylic acid methyl ester 

Relevant articles and documents

Lithium Bromide/Triethylamine Induced Cycloaddition of N-Alkylidene 2-Amino Esters and Amides to Electron-Deficient Olefins with High Regio- and Stereoselectivity

The imines of 2-amino esters and amides derived from glycine, alanine, and valine are deprotonated by the action of a lithium halide and triethylamine (or DBU).The resulting anionic intermediates undergo highly regio- and stereoselective cycloadditions with a variety of olefins activated by carbonyl-type substituents to produce stereochemically defined derivatives of proline esters or amides.The scope and limitations of this novel cycloaddition are discussed.