1132817-32-3

Basic information

• Product Name: 2-{3-[4-(5-methyl-1H-imidazol-1-yl)phenyl]-2-oxo-1,4-diazaspiro[4.4]non-3-en-1-yl}-N-[3-(trifluoromethyl)phenyl]acetamide
• Synonyms: 2-{3-[4-(5-methyl-1H-imidazol-1-yl)phenyl]-2-oxo-1,4-diazaspiro[4.4]non-3-en-1-yl}-N-[3-(trifluoromethyl)phenyl]acetamide
• CAS NO: 1132817-32-3
• Molecular Weight: 495.504
• Mol File: 1132817-32-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-{3-[4-(5-methyl-1H-imidazol-1-yl)phenyl]-2-oxo-1,4-diazaspiro[4.4]non-3-en-1-yl}-N-[3-(trifluoromethyl)phenyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{3-[4-(5-methyl-1H-imidazol-1-yl)phenyl]-2-oxo-1,4-diazaspiro[4.4]non-3-en-1-yl}-N-[3-(trifluoromethyl)phenyl]acetamide(1132817-32-3)
• EPA Substance Registry System: 2-{3-[4-(5-methyl-1H-imidazol-1-yl)phenyl]-2-oxo-1,4-diazaspiro[4.4]non-3-en-1-yl}-N-[3-(trifluoromethyl)phenyl]acetamide(1132817-32-3)

Safety Data

• Hazardous Substances Data: 1132817-32-3(Hazardous Substances Data)

Upstream product

• 1132817-67-4 3-[4-(4-methyl-1H-imidazol-1-yl)phenyl]-1,4-diazaspiro[4.4]non-3-en-2-one 
• 351-38-2 N-chloroacetyl-3-(trifluoromethyl)aniline 
• 950651-29-3 3-(4-bromophenyl)-1,4-diazaspiro[4.4]nonan-2-one 
• 167024-66-0 2-amino-2-(4-bromophenyl)acetonitrile 
• 98-16-8 3-trifluoromethylaniline 
• 1122-91-4 4-bromo-benzaldehyde 
• 1132817-68-5 3-[4-(5-methyl-1H-imidazol-1-yl)phenyl]-1,4-diazaspiro[4.4]non-3-en-2-one 
• 25625-57-4 2-bromo-N-(3′-(trifluoromethyl)phenyl)acetamide 

Relevant articles and documents

An efficient and scalable synthesis of the spirocyclic glycine transporter inhibitor GSK2137305

An efficient and scalable synthesis of a glycine transporter inhibitor is presented. The key steps in the synthetic sequence are the formation of a spirocyclic imidazolidinone from an -amino nitrile and a cyclic ketone and an arylation of 4-methyl imidazo