113290-07-6Relevant academic research and scientific papers
A tandem Aldol-Grob reaction of ketones with aromatic aldehydes
Kabalka, George W.,Tejedor, David,Li, Nan-Sheng,Malladi, Rama R.,Trotman, Sarah
, p. 15525 - 15532 (1998)
Aromatic aldehydes react with ketones to produce (E)-1-aryl-1-alkenesvia a tandem Aldol-Grob cleavage reaction sequence. The reaction, initiated by boron trifluoride, also produces a carboxylic acid fragment.
Radical addition of ethers to terminal alkynes with high E-selectivity
Chen, Ziii,Zhang, Yu-Xin,An, Yan,Song, Xin-Li,Wang, Ya-Hui,Zhu, Li-Li,Guo, Lin
supporting information; experimental part, p. 5146 - 5152 (2010/01/03)
Supporting information for this article is available on the WWW under http://dx.doi.org/10.1002/ejoc.200900858. Direct radical additions of ethers to terminal alkynes were investigated by using Me2Zn/O2 as radical initiator to afford 2-vinyl ether derivat
Protonation and Alkykation of 1-Arylpropenyl-lithium
Tanaka, Jiro,Nojima, Masatomo,Kusabayashi, Shigekazu,Nagase, Shigeru
, p. 673 - 678 (2007/10/02)
The protonation and alkylation of 1-arylpropenyl-lithium (1a-c) in ether was undertaken systematically; the regio- and stereo-chemistry being influenced by various factors.The characteristic features are as follows. (a) Protonation occurs predominantly at C-3, whereas the sterically more crowded C-1 is the more favoured site for alkylation, and (b) although 1-arylpropenyl-lithium (1) seems to exist mainly as the E-isomer, in some cases the product (3) or (5) having the Z-configuration is produced from attack at C-3 in a significant amount together with the E-isomer, e.g. protonation by oxygen acids in the presence or absence of tetramethylethylenediamine and methylation of the p-methoxy derivative (1a).
