113372-69-3

Basic information

• Product Name: 2-Chloro-4-AMinophenylalcohol
• Synonyms: 2-Chloro-4-AMinophenylalcohol;4-AMino-3-chloro-benzeneMethanol;BenzeneMethanol, 4-aMino-3-chloro-;(4-Amino-3-chlorophenyl)methanol
• CAS NO: 113372-69-3
• Molecular Formula: C₇H₈ClNO
• Molecular Weight: 157.59752
• Mol File: 113372-69-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 99 °C
• Boiling Point: 295.9±25.0 °C(Predicted)
• Appearance: /
• Density: 1.341±0.06 g/cm3(Predicted)
• PKA: 13.95±0.10(Predicted)
• CAS DataBase Reference: 2-Chloro-4-AMinophenylalcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-4-AMinophenylalcohol(113372-69-3)
• EPA Substance Registry System: 2-Chloro-4-AMinophenylalcohol(113372-69-3)

Safety Data

• Hazardous Substances Data: 113372-69-3(Hazardous Substances Data)

Usage

General Description

2-Chloro-4-Aminophenylalcohol is a chemical compound with the formula C7H8ClNO. It is a white to creamy white crystalline powder with a melting point of 90-93°C and a boiling point of 295-306°C. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used in the production of dyes and pigments, as well as in organic synthesis. 2-Chloro-4-Aminophenylalcohol is known to be a strong reducing agent and can react violently with oxidizing agents. It is important to handle this compound with caution and according to proper safety protocols.

Upstream product

• 620-20-2 1-Chloro-3-chloromethyl-benzene 
• 113372-67-1 3-chloro-4-nitrobenzyl benzoate 
• 77455-59-5 3-chloro-4-nitrobenzyl chloride 
• 2486-71-7 4-amino-3-chlorobenzoic acid 
• 21803-75-8 4-amino-3-chlorobenzonitrile 
• 84228-44-4 methyl 4-amino-3-chlorobenzoate 
• 113372-68-2 3-chloro-4-nitrobenzyl alcohol 

Downstream Products

• 253863-32-0 C₆₁H₆₉ClN₆O₂₀ 
• 253863-31-9 Carbonic acid 4-{(S)-6-allyloxycarbonylamino-2-[(S)-2-((R)-2-allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-hexanoylamino}-3-chloro-benzyl ester 4-nitro-phenyl ester 
• 253863-27-3 [(S)-5-[(S)-2-((R)-2-Allyloxycarbonylamino-propionylamino)-3-phenyl-propionylamino]-5-(2-chloro-4-hydroxymethyl-phenylcarbamoyl)-pentyl]-carbamic acid allyl ester 

Relevant articles and documents

Molybdenum hexacarbonyl and DBU reduction of nitro compounds under microwave irradiation

An ethanolic mixture of molybdenum hexacarbonyl and DBU mediates the reduction of nitroarenes to the corresponding anilines in excellent yields in 15-30 minutes under microwave irradiation. Georg Thieme Verlag Stuttgart.

New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities

The present invention relates to novel compounds having β2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.

THE SYNTHESIS OF 3-CHLORO-4-NITRO- AND 4-AMINO-3-CHLORO-BENZYL ALCOHOLS

The synthesis of the new compounds 3-chloro-4-nitro- and 4-amino-3-chloro-benzyl alcohols is described.Nitration of 3-chloro-benzyl chloride gives two isomers; the 3-chloro-4-nitrobenzyl chloride isomer is converted to the alcohol via an ester intermediat