113411-23-7

Basic information

• Product Name: 2-Thiazolesulfonamide,4-methyl-(9CI)
• Synonyms: 2-Thiazolesulfonamide,4-methyl-(9CI)
• CAS NO: 113411-23-7
• Molecular Formula: C4H6N2O2S2
• Molecular Weight: 178.23264
• Product Categories: SULFONAMIDE
• Mol File: 113411-23-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 375.1±35.0 °C(Predicted)
• Appearance: /
• Density: 1.518±0.06 g/cm3(Predicted)
• PKA: 9.16±0.60(Predicted)
• CAS DataBase Reference: 2-Thiazolesulfonamide,4-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiazolesulfonamide,4-methyl-(9CI)(113411-23-7)
• EPA Substance Registry System: 2-Thiazolesulfonamide,4-methyl-(9CI)(113411-23-7)

Safety Data

• Hazardous Substances Data: 113411-23-7(Hazardous Substances Data)

Upstream product

• 693-95-8 4-Methylthiazole 
• 1336-21-6 ammonium hydroxide 
• 459843-97-1 4-methyl-1,3-thiazole-2-sulfonyl chloride 
• 5685-06-3 4-methylthiazole-2(3H)-thione 

Relevant articles and documents

2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain 2-amino-N-(amino-oxo-aryl-λ6- sulfanylidene)acetamide compounds (referred to herein as ANASIA compounds) that, inter alia, inhibit (e.g., selectively inhibit) bacterial aminoacyl-tRNA synthetase (aaRS) (e.g., bacterial leucyl-tRNA synthetase, LeuRS). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit (e.g., selectively inhibit) bacterial aminoacyl-tRNA synthetase; to treat disorders that are ameliorated by the inhibition (e.g., selective inhibition) of bacterial aminoacyl-tRNA synthetase; to treat bacterial infections; etc.