113531-73-0

Upstream product

• 113461-83-9 (Z)-4-benzyl-1-<(benzyloxy)carbonyl>-6-<(2,4,5-trimethoxy-3-methylphenyl)methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione 
• 113461-84-0 (Z)-4-benzyl-1-(tert-butoxycarbonyl)-6-<(2,4,5-trimethoxy-3-methylphenyl)methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione 
• 113461-80-6 (Z)-4-benzyl-6-<(2,4,5-trimethoxy-3-methylphenyl)-methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione 
• 113461-91-9 (E)-3-benzyl-2-<(2,4,5-trimethoxy-3-methylphenyl)-methylene>-7,9,10-trimethoxy-8-methyl-4-oxo-1,2,3,4,5,6-hexahydro-1,5-imino-3-benzazocine-11-carboxylic acid isopropyl ester 
• 113461-86-2 4-Benzyl-2-hydroxy-5-oxo-6-(2,4,5-trimethoxy-3-methyl-benzyl)-3-[1-(2,4,5-trimethoxy-3-methyl-phenyl)-meth-(Z)-ylidene]-piperazine-1-carboxylic acid isopropyl ester 
• 113479-98-4 (Z)-4-benzyl-1-<(isopropyloxy)carbonyl>-6-<2,4,5-trimethoxy-3-methylphenyl)methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione 
• 50-00-0 formaldehyd 
• 113461-95-3 11-Benzyl-3,4,6-trimethoxy-5-methyl-12-[1-(2,4,5-trimethoxy-3-methyl-phenyl)-meth-(E)-ylidene]-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2⁽⁷⁾,3,5-trien-10-one 

Downstream Products

• 115678-28-9 3-<2-<(2,4,5-trimethoxy-3-methylphenyl)methyl>>-7,9,10-trimetoxy-8,11-dimethyl-3-(ethoxyoxalyl)-(1α,2α,5α)-1,2,3,4,5,6-hexahydro-1,5-imino-3-benzazocine 
• 112446-09-0 Butoxy-[(1S,9R,12R)-3,4,6-trimethoxy-5,13-dimethyl-12-(2,4,5-trimethoxy-3-methyl-benzyl)-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2⁽⁷⁾,3,5-trien-11-yl]-acetic acid butyl ester 
• 115678-27-8 2-<(2,4,5-trimethoxy-3-methylphenyl)methyl>-7,9,10-trimethoxy-8,11-dimethyl-3-(phthalimidoacetyl)-(1α,2α,5α)-1,2,3,4,5,6-hexahydro-1,5-imino-3-benzazocine 
• 112446-08-9 2-<(2,4,5-trimethoxy-3-methylphenyl)methyl>-7,9,10-trimethoxy-8,11-dimethyl-(1α,2α,5α)-1,2,3,4,5,6-hexahydro-1,5-imino-3-benzazocine 
• 66082-28-8 (+/-)-saframycin B 
• 112446-09-0 Butoxy-[(1S,9S,12S)-3,4,6-trimethoxy-5,13-dimethyl-12-(2,4,5-trimethoxy-3-methyl-benzyl)-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2⁽⁷⁾,3,5-trien-11-yl]-acetic acid butyl ester 
• 112446-08-9 (1S,9S,12S)-3,4,6-Trimethoxy-5,13-dimethyl-12-(2,4,5-trimethoxy-3-methyl-benzyl)-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2⁽⁷⁾,3,5-triene 
• 115792-74-0 (E)-3-benzyl-2-<(2,4,5-trimethoxy-3-methylphenyl)-methylene>-7,9,10-trimethoxy-8,11-dimethyl-1,2,3,4,5,6-hexahydro-1,5-imino-3-benzazocine 

Relevant academic research and scientific papers

A PROMISING CYCLIZATION OF THE 3-ARYLIDENE-6-ARYLMETHYL-2,5-PIPERAZINEDIONE TO CONSTRUCT TRICYCLIC LACTAM AS AN INTERMEDIATE TO SAFRAMYCIN SYNTHESIS

Regioselective reduction of the 3-arylidene-6-arylmethyl-2,5-piperazinedione (7b) at the C-2 position, followed by effective intramolecular cyclization to afford the tricyclic lactam (10b) is described.The structure of 16 as an intermediate to saframycin