113461-80-6

Basic information

• Product Name: (Z)-4-benzyl-6-<(2,4,5-trimethoxy-3-methylphenyl)-methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione
• Synonyms: (Z)-4-benzyl-6-<(2,4,5-trimethoxy-3-methylphenyl)-methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione
• CAS NO: 113461-80-6
• Molecular Weight: 590.673
• Mol File: 113461-80-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (Z)-4-benzyl-6-<(2,4,5-trimethoxy-3-methylphenyl)-methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-4-benzyl-6-<(2,4,5-trimethoxy-3-methylphenyl)-methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione(113461-80-6)
• EPA Substance Registry System: (Z)-4-benzyl-6-<(2,4,5-trimethoxy-3-methylphenyl)-methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione(113461-80-6)

Safety Data

• Hazardous Substances Data: 113461-80-6(Hazardous Substances Data)

Upstream product

• 106-51-4 p-benzoquinone 
• 113296-73-4 1,4-diacetyl-3-(2,4,5-trimethoxy-3-methylphenylmethyl)-2,5-piperazinedione 
• 113296-72-3 1-acetyl-3-(2,4,5-trimethoxy-3-methylphenyl)methyl-2,5-piperazinedione 
• 113296-74-5 (Z)-1-acetyl-3-(2,4,5-trimethoxy-3-methylphenylmethylene)-2,5-piperazinedione 
• 60059-09-8 2,4,5-trimethoxy-3-methylbenzaldehyde 
• 113296-75-6 (Z)-1-acetyl-6-(2,4,5-trimethoxy-3-methylphenylmethyl)-3-(2,4,5-trimethoxy-3-methylphenylmethylene)-2,5-piperazinedione 
• 100-39-0 benzyl bromide 
• 113461-83-9 (Z)-4-benzyl-1-<(benzyloxy)carbonyl>-6-<(2,4,5-trimethoxy-3-methylphenyl)methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione 
• 113461-82-8 (Z)-4-benzyl-1-(isobutylcarbonyl)-6-<(2,4,5-trimethoxy-3-methylphenyl)methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione 
• 113461-84-0 (Z)-4-benzyl-1-(tert-butoxycarbonyl)-6-<(2,4,5-trimethoxy-3-methylphenyl)methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione 
• 113479-98-4 (Z)-4-benzyl-1-<(isopropyloxy)carbonyl>-6-<2,4,5-trimethoxy-3-methylphenyl)methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione 
• 113461-81-7 (Z)-4-benzyl-1-(methoxycarbonyl)-6-<(2,4,5-trimethoxy-3-methylphenyl)methyl>-3-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-2,5-piperazinedione 
• 113461-79-3 (Z)-1-acetyl-4-benzyl-6-(2,4,5-trimethoxy-3-methylphenylmethyl)-3-(2,4,5-trimethoxy-3-methylphenylmethylene)-2,5-piperazinedione 
• 113296-80-3 (±)-(Z)-3-(2,4,5-trimethoxy-3-methylbenzyl)-6-(2,4,5-trimethoxy-3-methylbenzylidene)-2,5-piperazinedione 

Downstream Products

• 112446-08-9 2-<(2,4,5-trimethoxy-3-methylphenyl)methyl>-7,9,10-trimethoxy-8,11-dimethyl-(1α,2α,5α)-1,2,3,4,5,6-hexahydro-1,5-imino-3-benzazocine 
• 113461-93-1 (E)-3-benzyl-2-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-7,9,10-trimethoxy-8-methyl-4-oxo-1,2,3,4,5,6-hexahydro-1,5-imino-3-benzazocine-11-carboxylic acid benzyl ester 
• 113461-88-4 4-Benzyl-2-hydroxy-5-oxo-6-(2,4,5-trimethoxy-3-methyl-benzyl)-3-[1-(2,4,5-trimethoxy-3-methyl-phenyl)-meth-(Z)-ylidene]-piperazine-1-carboxylic acid benzyl ester 
• 113461-92-0 (E)-3-benzyl-2-<(2,4,5-trimethoxy-3-methylphenyl)methylene>-7,9,10-trimethoxy-8-methyl-4-oxo-1,2,3,4,5,6-hexahydro-1,5-imino-3-benzazocine-11-carboxylic acid isobutyl ester 
• 115678-27-8 2-<(2,4,5-trimethoxy-3-methylphenyl)methyl>-7,9,10-trimethoxy-8,11-dimethyl-3-(phthalimidoacetyl)-(1α,2α,5α)-1,2,3,4,5,6-hexahydro-1,5-imino-3-benzazocine 
• 113461-87-3 4-Benzyl-2-hydroxy-5-oxo-6-(2,4,5-trimethoxy-3-methyl-benzyl)-3-[1-(2,4,5-trimethoxy-3-methyl-phenyl)-meth-(Z)-ylidene]-piperazine-1-carboxylic acid isobutyl ester 
• 113461-96-4 11-Cyclohexylmethyl-3,4,6-trimethoxy-5-methyl-10-oxo-12-[1-(2,4,5-trimethoxy-3-methyl-phenyl)-meth-(E)-ylidene]-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2⁽⁷⁾,3,5-triene-13-carboxylic acid isopropyl ester 
• 113461-91-9 (E)-3-benzyl-2-<(2,4,5-trimethoxy-3-methylphenyl)-methylene>-7,9,10-trimethoxy-8-methyl-4-oxo-1,2,3,4,5,6-hexahydro-1,5-imino-3-benzazocine-11-carboxylic acid isopropyl ester 
• 113461-89-5 4-Benzyl-2-hydroxy-5-oxo-6-(2,4,5-trimethoxy-3-methyl-benzyl)-3-[1-(2,4,5-trimethoxy-3-methyl-phenyl)-meth-(Z)-ylidene]-piperazine-1-carboxylic acid tert-butyl ester 
• 113461-86-2 4-Benzyl-2-hydroxy-5-oxo-6-(2,4,5-trimethoxy-3-methyl-benzyl)-3-[1-(2,4,5-trimethoxy-3-methyl-phenyl)-meth-(Z)-ylidene]-piperazine-1-carboxylic acid isopropyl ester 
• 113461-90-8 (E)-3-benzyl-2-<(2,4,5-trimethoxy-3-methylphenyl)-methylene>-7,9,10-trimethoxy-8-methyl-4-oxo-1,2,3,4,5,6-hexahydro-1,5-imino-3-benzazocine-11-carboxylic acid methyl ester 
• 112446-09-0 Butoxy-[(1S,9R,12R)-3,4,6-trimethoxy-5,13-dimethyl-12-(2,4,5-trimethoxy-3-methyl-benzyl)-11,13-diaza-tricyclo[7.3.1.0^2,7]trideca-2⁽⁷⁾,3,5-trien-11-yl]-acetic acid butyl ester 
• 113461-85-1 4-Benzyl-2-hydroxy-5-oxo-6-(2,4,5-trimethoxy-3-methyl-benzyl)-3-[1-(2,4,5-trimethoxy-3-methyl-phenyl)-meth-(Z)-ylidene]-piperazine-1-carboxylic acid methyl ester 
• 113531-73-0 (E)-3-benzyl-2-<(2,4,5-trimethoxy-3-methylphenyl)-methylene>-7,9,70-trimethoxy-8,11-dimethyl-1,2,3,4,5,6-hexahydro-1,5-imino-3-benzazocine 

Relevant articles and documents

Stereoselective total synthesis of (±)-saframycin B

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A PROMISING CYCLIZATION OF THE 3-ARYLIDENE-6-ARYLMETHYL-2,5-PIPERAZINEDIONE TO CONSTRUCT TRICYCLIC LACTAM AS AN INTERMEDIATE TO SAFRAMYCIN SYNTHESIS

Regioselective reduction of the 3-arylidene-6-arylmethyl-2,5-piperazinedione (7b) at the C-2 position, followed by effective intramolecular cyclization to afford the tricyclic lactam (10b) is described.The structure of 16 as an intermediate to saframycin