1136-58-9

Basic information

• Product Name: (Z)-cyclohexyl(phenyl)methanone oxime
• CAS NO: 1136-58-9
• Molecular Formula: C₁₃H₁₇NO
• Molecular Weight: 203.2802
• Mol File: 1136-58-9.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 342.7°C at 760 mmHg
• Flash Point: 212.9°C
• Density: 1.08g/cm³
• Vapor Pressure: 2.83E-05mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: (Z)-cyclohexyl(phenyl)methanone oxime(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-cyclohexyl(phenyl)methanone oxime(1136-58-9)
• EPA Substance Registry System: (Z)-cyclohexyl(phenyl)methanone oxime(1136-58-9)

Safety Data

• Hazardous Substances Data: 1136-58-9(Hazardous Substances Data)

Usage

Description

(Z)-cyclohexyl(phenyl)methanone oxime, with the molecular formula C13H17NO, is an oxime derivative of cyclohexanone. It is a solid, white powder characterized by a melting point of 164-166°C and a boiling point of 325.4°C. This chemical compound is insoluble in water but readily soluble in organic solvents such as ethanol and acetone. It plays a significant role in organic synthesis and serves as a reagent in various chemical reactions.

Uses

Used in Pharmaceutical Production:
(Z)-cyclohexyl(phenyl)methanone oxime is used as an intermediate in the synthesis of pharmaceuticals for [application reason] its ability to be a building block in the creation of various compounds.
Used in Agrochemical Production:
(Z)-cyclohexyl(phenyl)methanone oxime is used as a component in the production of agrochemicals for [application reason] its utility in organic synthesis and as a reagent in chemical reactions.
Used in Organic Chemistry:
(Z)-cyclohexyl(phenyl)methanone oxime is used as a building block in organic chemistry for [application reason] its versatility in creating a wide range of compounds.
Used in Chemical Reactions:
(Z)-cyclohexyl(phenyl)methanone oxime is used as a reagent in chemical reactions for [application reason] its role in facilitating specific transformations and syntheses.

Upstream product

• 712-50-5 Cyclohexyl phenyl ketone 

Downstream Products

• 1006692-56-3 N-(cyclohexylidene(phenyl)methyl)acetamide 
• 23517-35-3 (Z)-cyclohexyl(phenyl)methanone oxime 
• 1759-68-8 N-benzoylcyclohexylamine 
• 2719-26-8 N-phenylcyclohexanamide 

Relevant articles and documents

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Photocatalyzed Triplet Sensitization of Oximes Using Visible Light Provides a Route to Nonclassical Beckmann Rearrangement Products

Oximes are valuable synthetic intermediates for the preparation of a variety of functional groups. To date, the stereoselective synthesis of oximes remains a major challenge, as most current synthetic methods either provide mixtures of E and Z isomers or furnish the thermodynamically preferred E isomer. Herein we report a mild and general method to achieve Z isomers of aryl oximes by photoisomerization of oximes via visible-light-mediated energy transfer (EnT) catalysis. Facile access to (Z)-oximes provides opportunities to achieve regio- and chemoselectivity complementary to those of widely used transformations employing oxime starting materials. We show an enhanced one-pot protocol for photocatalyzed oxime isomerization and subsequent Beckmann rearrangement that enables novel reactivity with alkyl groups migrating preferentially over aryl groups, reversing the regioselectivity of the traditional Beckmann reaction. Chemodivergent N- or O- cyclizations of alkenyl oximes are also demonstrated, leading to nitrones or cyclic oxime ethers, respectively.

APPLICATIONS OF N6-SUBSTITUTED ADENOSINE DERIVATIVE AND N6-SUBSTITUTED ADENINE DERIVATIVE TO CALMING, HYPNOSES, CONVULSION RESISTANCE, EPILEPTIC RESISTANCE, PARKINSON DISEASE RESISTANCE, AND DEMENTIA PREVENTION AND TREATMENT

PROBLEM TO BE SOLVED: To prepare analgesics, hypnotic agents, anticonvulsant agents, antiepileptics, antiparkinson drugs, dementia prophylactics, and health care food. SOLUTION: The present invention relates to an N6-substituted adenosine derivative and an N6-substituted adenine derivative selected from the group consisting of specific compounds. The present invention also relates to a pharmaceutical composition at least comprising a therapeutically effective amount of the compounds and a pharmaceutically acceptable carrier. The invention further relates to the compounds used in preparation of analgesics, hypnotic agents, anticonvulsant agents, antiepileptics, antiparkinson drugs, dementia prophylactics, and health care food. COPYRIGHT: (C)2016,JPO&INPIT