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113617-63-3

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113617-63-3 Usage

Brand Name(s) in US

Orbax

Uses

Different sources of media describe the Uses of 113617-63-3 differently. You can refer to the following data:
1. antibacterial
2. Orbifloxacin is a fluoroquinolone antibiotic used in veterinary medicine, mainly for the treatment of staphylococcal infections in dogs.

Brand name

Orbax (Schering-Plough Animal Health).

Veterinary Drugs and Treatments

Orbifloxacin is indicated for treatment in dogs and cats for bacterial infections susceptible to it. Orbifloxacin may also be of benefit in treating susceptible gram-negative infections in horses.

Check Digit Verification of cas no

The CAS Registry Mumber 113617-63-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,6,1 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 113617-63:
(8*1)+(7*1)+(6*3)+(5*6)+(4*1)+(3*7)+(2*6)+(1*3)=103
103 % 10 = 3
So 113617-63-3 is a valid CAS Registry Number.
InChI:InChI=1/C19H20F3N3O3/c1-8-5-24(6-9(2)23-8)17-14(21)13(20)12-16(15(17)22)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6H2,1-2H3,(H,27,28)/t8-,9+

113617-63-3 Well-known Company Product Price

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  • Sigma-Aldrich

  • (Y0001125)  Orbifloxacin  European Pharmacopoeia (EP) Reference Standard

  • 113617-63-3

  • Y0001125

  • 1,880.19CNY

  • Detail
  • USP

  • (1478673)  Orbifloxacin  United States Pharmacopeia (USP) Reference Standard

  • 113617-63-3

  • 1478673-350MG

  • 15,771.60CNY

  • Detail

113617-63-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Orbifloxacin

1.2 Other means of identification

Product number -
Other names 1-cyclopropyl-7-[(3S,5R)-3,5-dimethylpiperazin-1-yl]-5,6,8-trifluoro-4-oxoquinoline-3-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:113617-63-3 SDS

113617-63-3Downstream Products

113617-63-3Related news

Approaches for application of sub and supercritical fluid extraction for quantification of Orbifloxacin (cas 113617-63-3) from plasma and milk: Application to disposition kinetics08/23/2019

Since its extensive development in the early 1980s, SFE has attracted considerable attention as a sample-preparation procedure. However, other different sample preparation procedures, including precipitation, liquid- and/or solid-phase extraction in biological fluids, also remain in use. In this...detailed

In vitro antimicrobial activity of Orbifloxacin (cas 113617-63-3) against Staphylococcus intermedius isolates from canine skin and ear infections08/22/2019

The objective of the study was to evaluate the in vitro activity of orbifloxacin against Staphylococcus intermedius strains isolated in France from canine skin and ear infections. The minimum inhibitory concentrations (MICs) of orbifloxacin against 240 field S. intermedius isolates (69 skin and ...detailed

ArticlePharmacokinetics and Milk Penetration of Orbifloxacin (cas 113617-63-3) After Intravenous, Subcutaneous, and Intramuscular Administration to Lactating Goats08/21/2019

The single-dose disposition kinetics of orbifloxacin were determined in clinically normal lactating goats (n = 6) after intravenous, subcutaneous, and intramuscular administration of 2.5 mg of orbifloxacin/kg of body weight. Orbifloxacin concentrations were determined by HPLC with fluorescence d...detailed

Original articleDetermination of Orbifloxacin (cas 113617-63-3) in sheep plasma by high performance liquid chromatography with ultraviolet detection after intravenous and intramuscular administration08/20/2019

IntroductionSingle-dose pharmacokinetics of orbifloxacin (2.5 mg/kg body weight) were determined in clinically normal female Patanwadi sheep (n = 6) following intravenous and intramuscular administration.detailed

113617-63-3Relevant articles and documents

Preparation method of photoinitiator

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Paragraph 0074-0105, (2021/10/13)

The invention discloses a preparation method of a photoinitiator. The preparation method comprises the following steps: acid chloride required for Fries reaction, aluminum trichloride and a solvent are mixed and then subjected to a Fourier reaction with benzene. Fries reaction intermediate purification method The Fourier reaction intermediate is mixed with chlorine for chlorination reaction, and the product of the chlorination reaction is subjected to gas-liquid separation to separate the gas. Reaction Section Step and The product purification step results in a photoinitiator finished product. To the technical scheme of the invention, the advantages of the traditional process of producing the photoinitiator are combined with the characteristics of the microchannel reactor to realize continuous preparation, the productivity can be improved, the production risk is reduced, the manpower and equipment investment are reduced, and the cost is further reduced.

Synthesis method of photoinitiator 1-hydroxycyclohexyl phenyl ketone

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Paragraph 0023-0028, (2020/12/05)

The invention aims to solve the technical problems of an existing alpha-hydroxycyclohexyl phenyl ketone synthesis method, provides a synthesis method of a photoinitiator 1-hydroxycyclohexyl phenyl ketone, and belongs to the technical field of chemical synthesis. The synthesis method comprises the following steps: (1) reacting a halogenated benzene with magnesium particles to prepare a Grignard reagent, dropwise adding cyclohexylcarbonitrile into the prepared Grignard reagent, and after the reaction is completed, hydrolyzing to generate cyclohexyl phenyl ketone; and (2) reacting cyclohexyl phenyl ketone with chlorine to obtain 1-chlorocyclohexyl phenyl ketone, and carrying out a hydrolysis reaction on the 1-chlorocyclohexyl phenyl ketone and a sodium hydroxide aqueous solution under the action of a catalyst to obtain 1-hydroxycyclohexyl phenyl ketone. The method is simple in synthesis process, high in yield and suitable for industrial production.

A austria peso star synthetic method

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Paragraph 0019; 0022; 0025-0030, (2017/08/10)

The present invention discloses an orbifloxacin synthesis method, which comprises: adopting sparfloxacin as a raw material, carrying out a diazotization reaction under the effect of hydrochloric acid and sodium nitrite to obtain a diazonium salt solution, adding tetrafluoroboric acid to the diazonium salt solution in a dropwise manner, carrying out a fluorization reaction at a temperature of -10 DEG C, filtering the reaction solution after completing the reaction, taking the filter cake, washing with ethyl ether, drying, heating the dried product until no gas is generated to obtain an orbifloxacin crude product, and purifying the orbifloxacin crude product to obtain the orbifloxacin. According to the present invention, the sparfloxacin is utilized as the starting raw material and the diazotization reaction and the fluorization reaction are used to prepare the orbifloxacin, such that advantages of new process route, high product yield, low reaction cost and short reaction time are provided, and the method is the new economical and practical technology.

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