1137-90-2

Upstream product

• 51-21-8 5-fluorouracil 
• 930-69-8 sodium thiophenolate 
• 1820-81-1 5-chlorouracil 
• 51-20-7 5-bromouracil 
• 696-07-1 5-iodouracil 
• 66-22-8 uracil 
• 882-33-7 diphenyldisulfane 
• 1212-08-4 S-Phenyl benzenethiosulfonate 
• 108-98-5 thiophenol 

Downstream Products

• 135067-72-0 1-[(2-acetoxyethoxy)methyl]-5-phenylthiouracil 
• 1148106-10-8 5-phenylthio-2,4-dichloropyrimidine 
• 209908-59-8 trans-1-(4'-chloro-2'-buten-1'-yl)-5-(thiophenyl)uracil 
• 209908-65-6 cis-1-(4'-chloro-2'-buten-1'-yl)-5-(thiophenyl)uracil 

Relevant academic research and scientific papers

Thermal and Rhodium Acetate Catalyzed Reactions of 5-Diazouracil with Nucleophiles

In the presence of rhodium acetate 5-diazouracil reacts with varied secondary amines, azoles and thiols to give 5-substituted-uracils efficiently.

Photoinitiated Synthesis of Sulfides in Water

Herein, we report a synthetic route to obtain aryl sulfides using inexpensive and non-toxic reactants and water as solvent, that avoids the use of catalysts or heating. The photoinduced reaction between soluble substrates and a series of thiols in alkaline aqueous medium produces the corresponding sulfides in moderate to good yields.

Electrochemical synthesis method 5 - arylthiouracil compound

The invention discloses an electrochemical synthesis method of a 5-arylthiouracil compound. The method comprises the following steps: taking a hexafluoroisopropanol solution containing a uracil compound, aromatic thiophenol and iodized salt as an electrol

A NaI/H2O2-Mediated Sulfenylation and Selenylation of Unprotected Uracil and Its Derivatives

An efficient iodide-catalyzed/hydrogen peroxide mediated sulfenylation and selenylation of unprotected uracil and its derivatives with simple thiols and diselenides was established. This coupling tolerates a broad variety of functional groups to provide d

Method for preparing 5-sulfur/selenium-modified uracil derivative

The invention belongs to the field of organic chemistry and particularly relates to a method for efficiently preparing a 5-sulfur/selenium-modified uracil derivative. The method comprises the steps ofenabling a thiophenol compound shown as a formula I or

Recyclable iron/graphite catalyst for c-s cross coupling of thiols with aryl halides under ligand-free conditions

A recyclable iron/graphite (Fe/Cg) catalyst for the efficient C-S cross-coupling of various iodoarenes with aromatic/aliphatic thiols has been developed under ligand-free conditions (26 examples, up to 99% yield). The catalyst can be easily recovered and recycled up to seven cycles without loss of activity. Georg Thieme Verlag Stuttgart.

Facile route for the synthesis of nucleobase analogs

Various nucleobases, 5-heteroaryl substituted 2,4-alkoxy, and/or aryloxy pyrimidines were prepared in an easy method. Copyright Taylor & Francis Group, LLC.

Functionalization of unprotected uracil derivatives using the halogen - Magnesium exchange

The reaction of commercially available 5-iodouracil with 2 equiv of MeMgCl in the presence of LiCl, followed by the addition of i-PrMgCl-LiCl, provides the corresponding trimagnesiated species, which reacts with various electrophiles to give selectively 5

Synthesis of substituted uracils by the reactions of halouracils with selenium, sulfur, oxygen and nitrogen nucleophiles under focused microwave irradiation

Under microwave irradiation, the nucleophilic substitution reactions of halouracils with selenium, sulfur, oxygen and nitrogen nucleophiles was complete within several minutes with yields up to 99%. The method using microwave irradiation is superior to th

Efficient phenylsulfenylation and phenylselenenylation at the 5-position of uracil nucleosides with disulfide and diselenide mediated by [bis(trifluoroacetoxy)iodo] benzene

A series of uracil nucleosides reacted with diphenyl disulfide or diphenyl diselenide in the presence of hypervalent iodine reagent, [bis(trifluoroacetoxy)iodo]benzene, in acetonitrile to give the corresponding C-5 phenylsulfenylated or phenylselenenylate