1137486-95-3Relevant academic research and scientific papers
Palladium-catalyzed direct arylation of N-heteroarenes with arylsulfonyl hydrazides
Liu, Bo,Li, Jian,Song, Feijie,You, Jingsong
supporting information; experimental part, p. 10830 - 10833 (2012/09/22)
Hydrazides applied: A palladium-catalyzed direct Ci-H arylation of heteroarenes, with arylsulfonyl hydrazides as the arylating reagents, has been developed (see scheme). The reaction is chemoselective, in that arylsulfonyl hydrazides containing halogen substituents can be employed without participation of the halogen substituent in the reaction. The method offers a straightforward approach to a variety of aryl-heteroaryl compounds. Copyright
Discovery of a full-color-tunable fluorescent core framework through direct C-H (hetero)arylation of N-heterocycles
Liu, Bo,Wang, Zhi,Wu, Ningjie,Li, Mingliang,You, Jingsong,Lan, Jingbo
supporting information; experimental part, p. 1599 - 1603 (2012/03/10)
All the colors of the rainbow! A full coverage of emission wavelengths in the visible region (405-616 nm) with large Stokes shifts in C3-Indo-Fluor may be straightforwardly and succinctly achieved by the palladium-catalyzed direct C-H arylation of indolizines at the C3 position of the pyrrole ring (see figure). The fluorophores have successfully marked A375 cells. Copyright
Palladium-catalyzed desulfitative C-H arylation of heteroarenes with sodium sulfinates
Liu, Bo,Guo, Qiang,Cheng, Yangyang,Lan, Jingbo,You, Jingsong
supporting information; experimental part, p. 13415 - 13419 (2012/01/03)
Desulfitative C-H arylation: Palladium-catalyzed desulfitative C-H arylation of heteroarenes with sodium sulfinates has been disclosed to construct aryl-heteroaryl bonds without the need for any extra ligands (see scheme). Copyright
A palladium/copper bimetallic catalytic system: Dramatic improvement for Suzuki-Miyaura-type direct C-H arylation of azoles with arylboronic acids
Liu, Bo,Qin, Xurong,Li, Kaizhi,Li, Xiyu,Guo, Qiang,Lan, Jingbo,You, Jingsong
supporting information; experimental part, p. 11836 - 11839 (2011/01/12)
Bimetallic catalytic system: Palladium/copper bimetallic-catalyzed Suzuki-Miyaura-type coupling has been disclosed for direct C-H arylation of azoles, instead of azole halides or pseudohalides, with arylboronic acids (see scheme).
Phosphine-free, palladium-catalyzed arylation of heterocycles through C-H bond activation with pivalic acid as a cocatalyst
Zhao, Dongbing,Wang, Weida,Lian, Shuang,Yang, Fei,Lan, Jingbo,You, Jingsong
supporting information; experimental part, p. 1337 - 1340 (2009/09/04)
A new palladium-catalyzed methodology was developed for the direct C-arylation of azoles with a broad spectrum of aryl bromides without the presence of phosphines, the aid of CuI, or other metal additives by using pivalic acid as a cocatalyst. The method also allowed the direct C-arylation of the N-heterocycle N-oxides, and to a lesser degree, the perfluoroaromatics. It was also found that the method can not only be applied to the synthesis of 8-aryl-substituted caffeines, but also 8-arylated theophyllines and theobromines. The result showed thatthe method can tolerate an array of functional groups including ester, nitrile, nitro, aldehyde, methoxy, trifluoromethyl, fluoro, and chloro substituents, and can found its applications in a number of fields such as synthetic and medicinal chemistry both in industry and in academia.
