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4-Methoxyphenyl dimethylsulfamate is an organic compound with the chemical formula C9H13NO3S. It is a derivative of anisole, featuring a dimethylsulfamoyl group attached to the para position of the methoxyphenyl ring. 4-methoxyphenyl dimethylsulfamate is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals, particularly as a precursor in the production of sulfonamide-based drugs. The presence of the methoxy group provides additional functionality, which can be further modified in chemical reactions. 4-Methoxyphenyl dimethylsulfamate is typically synthesized through the reaction of 4-methoxyaniline with chlorosulfonic acid and dimethylamine. It is an important intermediate in the chemical industry due to its versatility in forming various sulfonamide derivatives, which have broad applications in medicine and agriculture.

1138-62-1

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1138-62-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1138-62-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,3 and 8 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1138-62:
(6*1)+(5*1)+(4*3)+(3*8)+(2*6)+(1*2)=61
61 % 10 = 1
So 1138-62-1 is a valid CAS Registry Number.

1138-62-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-dimethylsulfamate de 4-methoxyphenyle

1.2 Other means of identification

Product number -
Other names .4-methoxyphenyl dimethylsulfamate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1138-62-1 SDS

1138-62-1Relevant academic research and scientific papers

N -Arylation of (hetero)arylamines using aryl sulfamates and carbamates via C-O bond activation enabled by a reusable and durable nickel(0) catalyst

Dindarloo Inaloo, Iman,Majnooni, Sahar,Eslahi, Hassan,Esmaeilpour, Mohsen

, p. 13266 - 13278 (2020/10/07)

An effective and general aryl amination protocol has been developed using a magnetically recoverable Ni(0) based nanocatalyst. This new stable catalyst was prepared on Fe3O4@SiO2 modified by EDTA and investigated by FT-IR, EDX, TEM, XRD, DLS, FE-SEM, XPS, NMR, TGA, VSM, ICP and elemental analysis techniques. The reaction proceeded via carbon-oxygen bond cleavage of (hetero)aryl carbamates and sulfamates under simple and mild conditions without the use of any external ligands. This method demonstrated functional group tolerance in the N-arylation of various nitrogen-containing compounds as well as aliphatic amines, anilines, pyrroles, pyrazoles, imidazoles, indoles, and indazoles with good to excellent yields. Furthermore, the catalyst could be easily recovered by using an external magnetic field and directly reused at least six times without notable reduction in its activity. This journal is

Ni-Catalyzed Decarboxylative Cross-Coupling of Potassium Polyfluorobenzoates with Unactivated Phenol and Phenylmethanol Derivatives

Chen, Quan,Wu, Aizhen,Qin, Shengxiang,Zeng, Meiqi,Le, Zhiping,Yan, Zhaohua,Zhang, Hua

supporting information, p. 3239 - 3244 (2018/09/10)

A Ni-catalyzed decarboxylative cross-coupling of potassium polyfluorobenzoates with unactivated phenol and phenylmethanol derivatives is described. This novel transformation provides a practical and efficient protocol towards the synthesis of important polyfluorobiaryls and polyfluorinated diarylmethanes, and greatly enlarges the range of electrophiles utilized in decarboxylative coupling. Remarkably, preliminary mechanistic studies indicated the essential role of Zn(OAc)2 might lie in the enhancement of decarboxylation step. (Figure presented.).

Iron-catalyzed cross-coupling reactions of alkyl grignards with aryl sulfamates and tosylates

Agrawal, Toolika,Cook, Silas P.

supporting information, p. 96 - 99 (2013/03/28)

The iron-catalyzed cross-coupling of aryl sulfamates and tosylates has been achieved with primary and secondary alkyl Grignards. This study of iron-catalyzed cross-coupling reactions also examines the isomerization and β-hydride elimination problems that are associated with the use of isopropyl nucleophiles. While a variety of iron sources were competent in the reaction, the use of FeF3·3H2O was critical to minimize nucleophile isomerization.

Suzuki-Miyaura coupling of aryl carbamates, carbonates, and sulfamates

Quasdorf, Kyle W.,Riener, Michelle,Petrova, Krastina V.,Garg, Neil K.

supporting information; experimental part, p. 17748 - 17749 (2010/04/01)

(Chemical Equation Presented) The first Suzuki-Miyaura cross-couplings of carbamates, carbonates, and sulfamates is described. The method provides a powerful means of using simple derivatives of phenol as precursors to polysubstituted aromatic compounds, as exemplified by a concise synthesis of the anti-inflammatory drug flurbiprofen.

LES SYSTEMES BISPHASIQUES. 10. ALKYLATION DES ESTERS SULFAMIQUES EN CATALYSE PAR TRANSFERT DE PHASE: UNE NOUVELLE METHODE DE SYNTHESE DES SULFAMATES N-DISUBSTITUES

Beji, Mohamed,Hedayatullah, Mir

, p. 293 - 296 (2007/10/02)

We report here a new and simple method for the synthesis of the N,N-dimethylsulfamate esters of the general type R-O-SO2-N(CH3)2, in good yield, by direct alkylation of the corresponding unsubstituted sulfamate esters, by methyl iodide under solid-liquid

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