6265-92-5

Usage

Uses

Used in Research and Development:
2-(4-Methoxyphenyl)benzothiazole is used as a fluorescent dye for its yellow-green fluorescence, which aids in the visualization and tracking of molecules in biological and environmental studies.
Used in Polymer Science:
In the polymer industry, 2-(4-Methoxyphenyl)benzothiazole is used as a building block in the synthesis of other organic compounds, contributing to the development of new materials with specific properties.
Used in Biochemistry:
2-(4-Methoxyphenyl)benzothiazole serves as a fluorescent tracer in biochemistry, enabling researchers to study molecular interactions and processes within biological systems.
Used in Organic Synthesis:
As a key component in organic synthesis, 2-(4-Methoxyphenyl)benzothiazole is utilized to create a variety of organic compounds with diverse applications.
Used in Medical Imaging and Diagnostics:
2-(4-Methoxyphenyl)benzothiazole is being investigated for its potential use in medical imaging and diagnostics, where its fluorescent properties could enhance the detection and monitoring of diseases.
Used in Pharmaceutical Development:
2-(4-METHOXYPHENYL)BENZOTHIAZOLE has been studied for its potential anti-inflammatory and antioxidant properties, indicating its possible use in the development of pharmaceuticals for treating inflammation and oxidative stress-related conditions.

InChI:InChI=1/C14H11NOS/c1-16-11-8-6-10(7-9-11)14-15-12-4-2-3-5-13(12)17-14/h2-9H,1H3

Upstream product

• 3292-42-0 2-aminobenzenethiol hydrochloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 137-07-5 2-amino-benzenethiol 
• 26060-23-1 4-methoxy-N-phenylthiobenzamide 
• 3585-93-1 N-(4-methoxybenzylidene)aniline oxide 
• 76148-60-2 3-(4-methoxyphenyl)-2H-benzo[b][1,4]thiazin-2-one 
• 142505-34-8 N-(4-methoxyphenylmethylene)-2-phenylthiobenzenamine 
• 349614-89-7 N-(2-bromophenyl)-4-methoxybenzamide 
• 329939-01-7 N-(2-iodophenyl)-4-methoxybenzamide 
• 1141-88-4 2-Aminophenyl disulfide 
• 2746-25-0 p-Methoxybenzyl bromide 
• 824-94-2 p-methoxybenzyl chloride 
• 100-52-7 benzaldehyde 
• 95-16-9 1,3-Benzothiazole 

Downstream Products

• 1299483-59-2 4-(benzo[d]thiazol-2-yl)phenyl 4-(decyloxy)benzoate 
• 1299483-58-1 4-(benzo[d]thiazol-2-yl)phenyl 4-(octyloxy)benzoate 
• 1454287-81-0 (2-(benzo[d]thiazol-2-yl)-5-methoxyphenyl)(phenyl)methanone 
• 1610358-01-4 Ir(4-Me-2,3-dpq)2(pbt-OMe) 
• 1610357-99-7 Ir(pbt-OMe)2(4-Me-2,3-dpq) 
• 1454287-82-1 2-(benzo[d]thiazol-2-yl)-5-methoxy-1,3-phenylenebis(phenylmethanone) 

Relevant academic research and scientific papers

Novel synthesis of 2-arylbenzothiazoles mediated by ceric ammonium nitrate (CAN).

[reaction: see text] Cyclization of the intermediate radical formed after initial oxidative coupling between thiophenols and aromatic nitriles leads to the synthesis of a wide range of 2-arylbenzothiazoles.

RADIOLABELED COMPOUNDS

This invention relates to radiolabelled compounds as described herein, precursor compounds and reference compounds, as well as pharmaceutical compositions comprising the radiolabelled compounds, which are for use in a diagnostic method practised on the hu

Room temperature HFIP/Ag-promoted palladium-catalyzed C–H functionalization of benzothiazole with iodoarenes

A versatile synthetic protocol involving the room temperature direct arylation of benzothiazole with a wide variety of iodoarenes under Ag-promoted Pd-catalyzed conditions in HFIP as the reaction solvent has been presented. A sequential HFIP-promoted sele

A biomass-derived N-doped porous carbon catalyst for the aerobic dehydrogenation of nitrogen heterocycles

N-doped porous carbon (NC) was synthesized from sugar cane bagasse, which is a sustainable and widely available biomass waste. The preferred NC sample had a well-developed porous structure, a graphene-like surface morphology and different N species. More

Recyclable copper-catalyzed cyclization of o-haloanilides and metal sulfides: An efficient and practical access to substituted benzothiazoles

An efficient heterogeneous copper-catalyzed cyclization of o-haloanilides and metal sulfides has been achieved via the C–S coupling in DMF at 80 or 140 °C in the existence of an MCM-41-bound NHC-Cu(I) catalyst and then intramolecular condensation, delivering a wide range of substituted benzothiazoles in mostly good to high yields. This new MCM-41-NHC-CuI complex can facilely be obtained by a two-step procedure starting from easily accessible and inexpensive reagents and reused more than seven times without any significant loss of its catalytic efficiency. The present protocol has been successfully applied to the gram-scale synthesis of two antitumor agents 5F203 and PMX 610.

Ionic-Liquid-Catalyzed Synthesis of Imines, Benzimidazoles, Benzothiazoles, Quinoxalines and Quinolines through C?N, C?S, and C?C Bond Formation

We report the tetramethyl ammonium hydroxide catalyzed oxidative coupling of amines and alcohols for the synthesis of imines under metal-free conditions by utilizing oxygen from air as the terminal oxidant. Under the same conditions, with ortho-phenylene diamines and 2-aminobenzenethiols the corresponding benzimidazoles and benzothiazoles were obtained. Quinoxalines were obtained from ortho-phenylene diamines and 1-phenylethane-1,2-diol, the conditions were then extended to the synthesis of quinoline building blocks by reaction of 2-amino benzyl alcohols either with 1-phenylethan-1-ol or acetophenone derivatives. The formation of C?N, C?S and C?C bonds was achieved under metal-free conditions. A broad range of amines (aromatic, aliphatic, cyclic and heteroaromatic) as well as benzylic alcohols including heteroaryl alcohols reacted smoothly and provided the desired products. The mild reaction conditions, commercially available catalyst, metal-free, good functional-group tolerance, broad range of products (imines, benzimidazoles, benzothiazoles, quinoxalines and quinolines) and applicability at gram scale reactions are the advantages of the present strategy.

Photocatalytic green synthesis of benzazoles from alcohol oxidation/toluene sp3C-H activation over metal-free BCN: effect of crystallinity and N-B pair exposure

Porous borocarbonitride (P-BCN), with the characteristics of enhanced crystallinity and improved N-B pair exposure, was prepared with a simple KCl-assisted molten salt strategy. Efficient heterogeneous photocatalytic tandem synthesis of benzazoles from alcohol oxidation/toluene sp3C-H activation was achieved firstly over the metal-free P-BCN using visible light and the green oxidant O2, with only water as a by-product. Variouso-thio/hydroxy/aminoanilines and alcohols or toluenes could be converted to the corresponding 2-substituted benzothiazoles, benzoxazoles and benzimidazoles with good to excellent photocatalytic performance. The improved photocatalytic performance in comparison to bulk BCN should be due to the crystallinity-enhancement-induced improvement in charge separation and transmission. The increased N-B pair exposure promoted superoxide radical generation due to the electron-enriched N atoms, as well as improved oxidation ability due to the valence band constructed by the B 2p orbital. This work presents a green and efficient synthetic strategy towards benzazoles and other fine chemicalsviametal-free heterogeneous photocatalysis.

Method for catalytically synthesizing benzothiazole compound by using copper complex

The invention relates to a method for catalytically synthesizing benzothiazole compounds by using a copper complex, which is characterized in that a copper complex containing ortho-carborane Schiff base ligand is used as a catalyst to form aldehydes. 2 - Bromoaniline and sodium sulfide are used as raw materials, and the reaction is carried out at room temperature to obtain a benzothiazole compound. Compared with the prior art, the copper complex catalytic aldehyde, 2 -bromoaniline and sodium sulfide (Na) containing the ortho-carborane Schiff base ligand are utilized. 2 Multiple components of S) react to prepare benzothiazole compounds, and the catalyst is low in dosage, mild in reaction conditions, high in reaction rate, high in yield, wide in substrate range, cheap and accessible in raw materials and wide in application prospect in industry.

ZnO-NPs catalyzed condensation of 2-aminothiophenol and aryl/alkyl nitriles: Efficient green synthesis of 2-substituted benzothiazoles

The synthesis of 2-substituted benzothiazoles has been described using ZnO-nanoparticles as a catalyst. The condensation of 2-aminothiophenol and aryl/alkyl nitriles resulted in the formation of various 2-substituted benzothiazoles under solvent-free reaction conditions. The library of 2-substituted benzothiazoles has been synthesized in good to excellent yield. The reaction has shown a wide range of functional group compatibility for both varyingly substituted 2-aminothiophenols and nitriles. The protocol has many advantages such as faster reaction rate, mild reaction conditions, various functional group compatibility, excellent yield, solvent-free reaction conditions, easy recovery of materials, and excellent catalyst recyclability, among others. The various advantages of this protocol make it a more feasible, economical, and environmentally benign process.

An efficient rapid synthesis of benzoxazoles and benzothiazoles using pma.Sio2 at room temperature under heterogeneous conditions

Treatment of 2-aminophenol (or 2-aminothiophenol) with aromatic aldehydes in the presence of phosphomolybdic acid on silica at room temperature affords the corresponding benzoxazoles (or benzothiazoles) in excellent yields (88-96%) under heterogeneous conditions. Benzoxazoles and benzothiazoles are formed in less than 10 min.