6265-92-5

Usage

Uses

Used in Research and Development:
2-(4-Methoxyphenyl)benzothiazole is used as a fluorescent dye for its yellow-green fluorescence, which aids in the visualization and tracking of molecules in biological and environmental studies.
Used in Polymer Science:
In the polymer industry, 2-(4-Methoxyphenyl)benzothiazole is used as a building block in the synthesis of other organic compounds, contributing to the development of new materials with specific properties.
Used in Biochemistry:
2-(4-Methoxyphenyl)benzothiazole serves as a fluorescent tracer in biochemistry, enabling researchers to study molecular interactions and processes within biological systems.
Used in Organic Synthesis:
As a key component in organic synthesis, 2-(4-Methoxyphenyl)benzothiazole is utilized to create a variety of organic compounds with diverse applications.
Used in Medical Imaging and Diagnostics:
2-(4-Methoxyphenyl)benzothiazole is being investigated for its potential use in medical imaging and diagnostics, where its fluorescent properties could enhance the detection and monitoring of diseases.
Used in Pharmaceutical Development:
2-(4-METHOXYPHENYL)BENZOTHIAZOLE has been studied for its potential anti-inflammatory and antioxidant properties, indicating its possible use in the development of pharmaceuticals for treating inflammation and oxidative stress-related conditions.

InChI:InChI=1/C14H11NOS/c1-16-11-8-6-10(7-9-11)14-15-12-4-2-3-5-13(12)17-14/h2-9H,1H3

Upstream product

• 3292-42-0 2-aminobenzenethiol hydrochloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 137-07-5 2-amino-benzenethiol 
• 100-07-2 4-methoxy-benzoyl chloride 
• 57774-72-8 ethyl p-methoxy-phenyl-carbothionylcarbamate 
• 68090-03-9 4-methoxy-selenobenzamide 
• 105-64-6 diisopropyl peroxydicarbonate 
• 142505-39-3 N-(4-methoxyphenylmethylene)-2-methylthiobenzenamine 
• 3585-93-1 N-(4-methoxybenzylidene)aniline oxide 
• 100-09-4 4-methoxybenzoic acid 
• 108-98-5 thiophenol 
• 874-90-8 4-methoxybenzonitrile 
• 14063-79-7 (Z)-3-chloro-3-(4-methoxyphenyl)acrylaldehyde 
• 1155-00-6 bis(2-nitrophenyl)disulfide 

Downstream Products

• 21223-49-4 N-methyl-2-(4-methoxyphenyl)benzothiazolium iodide 
• 53544-70-0 2-(4-methoxyphenyl)-6-nitrobenzothiazole 
• 6265-55-0 2-(4-hydroxyphenyl)benzothiazole 
• 1454287-81-0 (2-(benzo[d]thiazol-2-yl)-5-methoxyphenyl)(phenyl)methanone 
• 1299483-59-2 4-(benzo[d]thiazol-2-yl)phenyl 4-(decyloxy)benzoate 
• 1299483-58-1 4-(benzo[d]thiazol-2-yl)phenyl 4-(octyloxy)benzoate 

Relevant academic research and scientific papers

Novel synthesis of 2-arylbenzothiazoles mediated by ceric ammonium nitrate (CAN).

[reaction: see text] Cyclization of the intermediate radical formed after initial oxidative coupling between thiophenols and aromatic nitriles leads to the synthesis of a wide range of 2-arylbenzothiazoles.

RADIOLABELED COMPOUNDS

This invention relates to radiolabelled compounds as described herein, precursor compounds and reference compounds, as well as pharmaceutical compositions comprising the radiolabelled compounds, which are for use in a diagnostic method practised on the hu

Room temperature HFIP/Ag-promoted palladium-catalyzed C–H functionalization of benzothiazole with iodoarenes

A versatile synthetic protocol involving the room temperature direct arylation of benzothiazole with a wide variety of iodoarenes under Ag-promoted Pd-catalyzed conditions in HFIP as the reaction solvent has been presented. A sequential HFIP-promoted sele

A biomass-derived N-doped porous carbon catalyst for the aerobic dehydrogenation of nitrogen heterocycles

N-doped porous carbon (NC) was synthesized from sugar cane bagasse, which is a sustainable and widely available biomass waste. The preferred NC sample had a well-developed porous structure, a graphene-like surface morphology and different N species. More

Recyclable copper-catalyzed cyclization of o-haloanilides and metal sulfides: An efficient and practical access to substituted benzothiazoles

An efficient heterogeneous copper-catalyzed cyclization of o-haloanilides and metal sulfides has been achieved via the C–S coupling in DMF at 80 or 140 °C in the existence of an MCM-41-bound NHC-Cu(I) catalyst and then intramolecular condensation, delivering a wide range of substituted benzothiazoles in mostly good to high yields. This new MCM-41-NHC-CuI complex can facilely be obtained by a two-step procedure starting from easily accessible and inexpensive reagents and reused more than seven times without any significant loss of its catalytic efficiency. The present protocol has been successfully applied to the gram-scale synthesis of two antitumor agents 5F203 and PMX 610.

KOtBu-Promoted Halogen-Bond-Assisted Intramolecular C-S Cross-Coupling of o-Iodothioanilides for the Synthesis of 2-Substituted Benzothiazoles

An efficacious and mild KOtBu-promoted intramolecular C-S cross-coupling of ortho-iodothioanilides in conjunction with a catalytic quantity of phenanthroline as an additive has been described for the convenient synthesis of 2-substituted benzothiazoles. The methodology is suitable for attaining a wide variety of 2-alkyl- and 2-aryl-substituted benzothiazoles. Single-crystal XRD, DFT calculations, NMR, and UV studies suggest that halogen bonds between the units of ortho-iodothioanilides may assist in the electron transfer process.

Photocatalyst- And Transition-Metal-Free Visible-Light-Promoted Intramolecular C(sp2)-S Formation

A photocatalyst- and transition-metal-free visible-light-induced cyclization of ortho-halothiobenzanilides has been developed. Upon irradiation with visible light, substrates undergo dehalogenative cyclization to 2-aryl benzothiazoles with high efficiency and selectivity. This photocyclization exhibits a high tolerance to various functional groups, is applicable for the synthesis of 2-alkyl benzothiazoles, and is easy to set up for gram-scale reaction.

Visible-Light Carbon Nitride-Catalyzed Aerobic Cyclization of Thiobenzanilides under Ambient Air Conditions

A metal-free heterogeneous photocatalysis has been developed for the synthesis of benzothiazoles via intramolecular C-H functionalization/C-S bond formation of thiobenzanilides by inexpensive graphitic carbon nitride (g-C3N4) under visible-light irradiation. This reaction provides access to a broad range of 2-substituted benzothiazoles in high yields under an air atmosphere at room temperature without addition of a strong base or organic oxidizing reagents. In addition, the catalyst was found to be stable and reusable after five reaction cycles.

Method for catalytically synthesizing benzothiazole compound by using copper complex

The invention relates to a method for catalytically synthesizing benzothiazole compounds by using a copper complex, which is characterized in that a copper complex containing ortho-carborane Schiff base ligand is used as a catalyst to form aldehydes. 2 - Bromoaniline and sodium sulfide are used as raw materials, and the reaction is carried out at room temperature to obtain a benzothiazole compound. Compared with the prior art, the copper complex catalytic aldehyde, 2 -bromoaniline and sodium sulfide (Na) containing the ortho-carborane Schiff base ligand are utilized. 2 Multiple components of S) react to prepare benzothiazole compounds, and the catalyst is low in dosage, mild in reaction conditions, high in reaction rate, high in yield, wide in substrate range, cheap and accessible in raw materials and wide in application prospect in industry.

ZnO-NPs catalyzed condensation of 2-aminothiophenol and aryl/alkyl nitriles: Efficient green synthesis of 2-substituted benzothiazoles

The synthesis of 2-substituted benzothiazoles has been described using ZnO-nanoparticles as a catalyst. The condensation of 2-aminothiophenol and aryl/alkyl nitriles resulted in the formation of various 2-substituted benzothiazoles under solvent-free reaction conditions. The library of 2-substituted benzothiazoles has been synthesized in good to excellent yield. The reaction has shown a wide range of functional group compatibility for both varyingly substituted 2-aminothiophenols and nitriles. The protocol has many advantages such as faster reaction rate, mild reaction conditions, various functional group compatibility, excellent yield, solvent-free reaction conditions, easy recovery of materials, and excellent catalyst recyclability, among others. The various advantages of this protocol make it a more feasible, economical, and environmentally benign process.