113886-72-9

Basic information

• Product Name: 2'-O-methyl-2-thiouridine
• Synonyms: 2'-O-methyl-2-thiouridine
• CAS NO: 113886-72-9
• Molecular Formula: C₁₀H₁₄N₂O₅S
• Molecular Weight: 274.29356
• Mol File: 113886-72-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Density: 1.55±0.1 g/cm3(Predicted)
• PKA: 6.97±0.20(Predicted)
• CAS DataBase Reference: 2'-O-methyl-2-thiouridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-O-methyl-2-thiouridine(113886-72-9)
• EPA Substance Registry System: 2'-O-methyl-2-thiouridine(113886-72-9)

Safety Data

• Hazardous Substances Data: 113886-72-9(Hazardous Substances Data)

Upstream product

• 68045-07-8 1,3,5-tri-O-benzoyl-2-O-methyl-α-D-ribofuranose 
• 75-09-2 dichloromethane 
• 7553-56-2 iodine 
• 1352173-49-9 2'-O-Me-2'-O-ethyluridine 
• 1613530-35-0 C₁₁H₁₆N₂O₈S 
• 2140-76-3 2'-O-methyluridine 
• 302918-82-7 3-Benzoyl-1-((2R,3R,3aR,9aR)-5,5,7,7-tetraisopropyl-3-methoxy-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 302918-81-6 3-Benzoyl-1-((2R,3R,3aS,9aR)-3-hydroxy-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 302918-80-5 1-((2R,3R,3aS,9aR)-3-Hydroxy-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 20235-78-3 2-thiouridine 
• 155006-24-9 1-(3,5-di-O-benzoyl-2-O-methyl-β-D-ribofuranosyl)-2-thio-4-(1H,3H)-pyrimidinone 

Relevant articles and documents

Alternative nucleic acid molecules and uses thereof

The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.

ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF

The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.

A New Route to 2′-O-Alkyl-2-thiouridine Derivatives via 4-O-Protection of the Uracil Base and Hybridization Properties of Oligonucleotides Incorporating These Modified Nucleoside Derivatives

Oligonucleotides containing 2-thiouridine (s2U) in place of uridine form stable RNA duplexes with complementary RNAs. Particularly, this modified nucleoside has proved to recognize highly selectively adenosine, the genuine partner, without form