113931-96-7

Basic information

• Product Name: 4-<(tert-butyldimethylsilyl)oxy>-3-methoxybenzyl alcohol
• Synonyms: 4-<(tert-butyldimethylsilyl)oxy>-3-methoxybenzyl alcohol
• CAS NO: 113931-96-7
• Molecular Weight: 268.428
• Mol File: 113931-96-7.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: 4-<(tert-butyldimethylsilyl)oxy>-3-methoxybenzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-<(tert-butyldimethylsilyl)oxy>-3-methoxybenzyl alcohol(113931-96-7)
• EPA Substance Registry System: 4-<(tert-butyldimethylsilyl)oxy>-3-methoxybenzyl alcohol(113931-96-7)

Safety Data

• Hazardous Substances Data: 113931-96-7(Hazardous Substances Data)

Upstream product

• 139-85-5 3,4-dihydroxybenzaldehyde 
• 121-33-5 vanillin 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 69404-94-0 O-tert-butyldimethylsilylvanillin 
• 139140-12-8 tert-butyl(4-(tert-butyldimethylsilyloxy)-3-methoxybenzyloxy)dimethylsilane 
• 498-00-0 4-hydroxymethyl-2-methoxyphenol 

Downstream Products

• 1264253-79-3 2-trimethylstannyl-4-(O-silyldimethyl-tert-butyl)-3-methoxybenzyl alcohol 
• 1264669-05-7 HOCH₂C₆H₂(OCH₃)(OSi(CH₃)(C(CH₃)3)CH₂Sn(CH₃)3)Sn(CH₃)3 
• 63357-45-9 2-acetamido-3-(4-hydroxy-3-methoxyphenyl)propanoic acid 
• 300-48-1 3-O-methyldopa 
• 1073340-76-7 4-tert-butyldimethylsilyloxy-3-methoxybenzyl hexadecanoate 
• 1073340-75-6 4-tert-butyldimethylsilyloxy-3-methoxybenzyl tetradecanoate 
• 1073340-69-8 4-tert-butyldimethylsilyloxy-3-methoxybenzyl octanoate 
• 1073340-68-7 4-tert-butyldimethylsilyloxy-3-methoxybenzyl heptanoate 
• 1073340-65-4 4-tert-butyldimethylsilyloxy-3-methoxybenzyl butanoate 
• 131119-10-3 Vanillyl nonanoate 
• 106727-89-3 4-hydroxy-3-methoxybenzyl hexadecanoate 
• 57404-55-4 4-acetoxymethyl-2-methoxyphenol 
• 916911-63-2 4-hydroxy-3-methoxybenzyl heptanoate 
• 1073340-79-0 4-hydroxy-3-methoxybenzyl pentanoate 

Relevant articles and documents

A simple and Highly Chemoselective Desilylation of tert-Butyldimethylsilyl Ethers

The use of a 0.25M CH3OH/CCl4 (1:1) solvent mixture under ultrasound for the selective deprotection of tert-butyldimethylsilyl ethers of benzyl alcohols is described.This method enables to deprotect tert-butyldimethylsilyl ethers of primary alcohols, whereas tert-butyldimethylsilyl ethers of secondery and tertiary alcohols were stable under the reaction condition.

Free-radical-scavenging and xanthine oxidase inhibitory constituents from Stereospermum personatum

Bioassay-guided fractionation of different extracts of both stem and stem bark of Stereospermum personatum led to the isolation of free-radical-scavenging and xanthine oxidase inhibitory molecules along with three new anthraquinones, sterequinones F-H (1-3), a new naphthoquinone, sterequinone I (4), two new phenethyl esters, 2(4′-hydroxyphenyl)ethyl undecanoate (14) and 2(4′-hydroxyphenyl)ethyl nonacosanoate (15), and a new 3,4,5-trimethoxycinnamyl ether, 2-methoxy-4-[3′-(3″,4″, 5″trimethoxyphenyl)allyloxymethyl]phenol (16), together with known compounds. The antioxidant and xanthine oxidase inhibitory potentials of the isolated compounds are reported.

Chromium-Salen Complex/Nitroxyl Radical Cooperative Catalysis: A Combination for Aerobic Intramolecular Dearomative Coupling of Phenols

We describe an aerobic intramolecular dearomative coupling reaction of tethered phenols using a catalytic system consisting of a chromium-salen (Cr-salen) complex combined with a nitroxyl radical. This novel catalytic system enables formation of various spirocyclic dienone products including those unable to be accessed by previously reported methods efficiently under mild reaction conditions.

A mild, efficient, and selective deprotection of tert-butyldimethylsilyl (TBDMS) ethers using dicationic ionic liquid as a catalyst

Selective deprotection of alkyl TBDMS ether in the presence of phenolic TBDMS ether using dicationic ionic liquid [tetraEG(mim)2][OMs] 2 as a homogeneous catalyst showed significant catalytic activity in methanol at ambient temperature to produce respective alcohol in excellent yield. The present environmentally benign catalytic system is found to be very convenient, fast, high yielding, and clean method for selective desilylation of alkyl silyl ethers even in the existence of other sensitive organic functional groups such as aldehyde, methoxy, and acetate were also achieved.