1140-53-0

Usage

General Description

2,2-dichloro-N-(naphthalen-1-yl)acetamide is a chemical compound with the molecular formula C12H10Cl2NO. It is a derivative of acetamide, containing two chlorine atoms and a naphthalene moiety. 2,2-dichloro-N-(naphthalen-1-yl)acetamide is commonly used as a biocide and antimicrobial agent in various industrial and agricultural applications. It functions by inhibiting the growth of microorganisms and bacteria and is often found in products such as preservatives, disinfectants, and pesticides. The use of 2,2-dichloro-N-(naphthalen-1-yl)acetamide is regulated in many countries due to its potential environmental and health risks, and it is important to handle and dispose of this chemical with caution.

Upstream product

• 75-09-2 dichloromethane 
• 86-84-0 1-Naphthyl isocyanate 
• 134-32-7 1-amino-naphthalene 

Relevant academic research and scientific papers

Dichloromeldrum's acid (DiCMA): A practical and green amine dichloroacetylation reagent

Dichloromeldrum's acid is introduced as a bench-stable, nonvolatile reagent for the dichloroacetylation of anilines and alkyl amines to produce α,α-dichloroacetamides, which are important motifs for medicinal chemistry. Products are formed in good to excellent yields with reagent grade solvents, and, as the only byproducts are acetone and CO2, no column chromatography is required. Thus, this reagent is practical, efficient, and green for the dichloroacetylation of primary amines.

Homologation of isocyanates with lithium carbenoids: A straightforward access to α-halomethyl- and α,α-dihalomethylamides

Treatment of widely available isocyanates with monohalolithium and dihalolithium carbenoids provides a valuable protocol for the one-pot preparation of α-halo- and α,α-dihaloacetamide derivatives. While monohalolithium carbenoids can be prepared by a smoo