1140280-85-8Relevant articles and documents
Stereoselective Synthesis of β-Lactam-triflones under Catalyst-Free Conditions
Huang, Zhongyan,Wang, Chen,Tokunaga, Etsuko,Sumii, Yuji,Shibata, Norio
, p. 5610 - 5613 (2015)
The first example of the synthesis of β-lactam-triflones is described. Treatment of 2-diazo-1-aryl-2-(trifluoromethylsulfonyl)ethanones 1c-f with imines 2 under catalyst-free heating conditions provides pharmaceutically attractive multisubstituted β-lacta
Anionic Triflyldiazomethane: Generation and Its Application for Synthesis of Pyrazole-3-triflones via [3 + 2] Cycloaddition Reaction
Das, Pulakesh,Gondo, Satoshi,Tokunaga, Etsuko,Sumii, Yuji,Shibata, Norio
, p. 558 - 561 (2018)
The synthesis of pyrazole triflones containing a triflyl group at the 3-position is disclosed. Treatment of 2-diazo-1-phenyl-2-((trifluoromethyl)sulfonyl)ethan-1-one with nitroalkenes under basic conditions gave pharmaceutically attractive pyrazole 3-triflones in good to high yields. The generation of anionic triflyldiazomethane species followed by the [3 + 2] cycloaddition reaction with nitroalkenes is proposed for this transformation. 3-(Difluoromethanesulfonyl)pyrazoles were also synthesized by using a previously unknown anionic (difluoromethanesulfonyl)diazomethane species under a similar strategy.
Synthesis of stable arsonium and sulfur ylides from perfluoroalkanesulfonyl diazocarbonyl compounds and their X-ray diffraction analysis
Pang, Wan,Zhu, Shifa,Xing, Chunhui,Luo, Nianhua,Jiang, Huanfeng,Zhu, Shizheng
, p. 343 - 348 (2008/12/22)
A series of stable fluorine-containing arsonium ylides and sulfur ylides were simply synthesized from perfluoroalkanesulfonyl diazocarbonyl compounds in the presence of rhodium catalyst. The ylide products are fairly stable due to the strong electron-withdrawing properties of perfluoroalkanesulfonyl group and carbonyl group. They are fully confirmed by spectral methods and the structures of 3ba and 3cd are also established by X-ray single crystal diffraction analysis. Several interesting features about the ylide structures and some weak fluorine interaction between them are described here.
