1140496-10-1

Basic information

• Product Name: (R)-4-(4-chlorobenzyl)-3-methyl-5-(pyrrolidin-2-yl)-4H-1,2,4-trazole hydrochloride
• Synonyms: (R)-4-(4-chlorobenzyl)-3-methyl-5-(pyrrolidin-2-yl)-4H-1,2,4-trazole hydrochloride
• CAS NO: 1140496-10-1
• Molecular Weight: 313.23
• Mol File: 1140496-10-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-(4-chlorobenzyl)-3-methyl-5-(pyrrolidin-2-yl)-4H-1,2,4-trazole hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-(4-chlorobenzyl)-3-methyl-5-(pyrrolidin-2-yl)-4H-1,2,4-trazole hydrochloride(1140496-10-1)
• EPA Substance Registry System: (R)-4-(4-chlorobenzyl)-3-methyl-5-(pyrrolidin-2-yl)-4H-1,2,4-trazole hydrochloride(1140496-10-1)

Safety Data

• Hazardous Substances Data: 1140496-10-1(Hazardous Substances Data)

Upstream product

• 1140495-89-1 (R)-tert-butyl 2-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidine-1-carboxylate 

Downstream Products

• 1140489-56-0 (R)-2-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)-N-(4-(trifluoromethyl)phenyl)pyrrolidine-1-carboxamide 
• 1140492-42-7 2-[4-(4-chloro-benzyl)-5-methyl-4H-[1,2,4]triazol-3-yl]-pyrrolidine-1-carboxylic acid (2-chloro-4-methyl-pyrimidin-5-yl)-amide 
• 1140911-22-3 (R,E)-2-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)-N'-cyano-N-(4-(trifluoromethyl)phenyl)pyrrolidine-1-carboxamidine 
• 1140489-96-8 (R)-2-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)-N-(4-chloro-2-fluorophenyl)pyrrolidine-1-carboxamide 
• 1140490-34-1 (R)-4-chlorophenyl-2-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidine-1-carboxylate 
• 1140490-16-9 (R)-2-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)-N-(4-chlorophenyl)pyrrolidine-1-carboxamide 
• 1140494-63-8 (R)-3-(2-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidin-1-yl)-4-(4-chloro-2-fluorophenylamino)cyclobut-3-ene-1,2-dione 
• 1140490-32-9 (R)-1-(2-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrrolidin-1-yl)-2-(4-(trifluoromethyl)phenyl)ethanone 

Relevant articles and documents

Novel pyrrolidine heterocycles as CCR1 antagonists

A novel series of pyrrolidine heterocycles was prepared and found to show potent inhibitory activity of CCR1 binding and CCL3 mediated chemotaxis of a CCR1-expressing cell line. A potent, optimized triazole lead from this series was found to have acceptab