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1141-06-6

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1141-06-6 Usage

Chemical Properties

ORANGE TO BROWN CRYSTALLINE POWDER

Check Digit Verification of cas no

The CAS Registry Mumber 1141-06-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,4 and 1 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1141-06:
(6*1)+(5*1)+(4*4)+(3*1)+(2*0)+(1*6)=36
36 % 10 = 6
So 1141-06-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H10N2O2/c15-11(9-5-1-3-7-13-9)12(16)10-6-2-4-8-14-10/h1-8,11,15H/t11-/m1/s1

1141-06-6 Well-known Company Product Price

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  • Aldrich

  • (P65401)  α-Pyridoin  99%

  • 1141-06-6

  • P65401-25G

  • 611.91CNY

  • Detail

1141-06-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-hydroxy-1,2-dipyridin-2-ylethanone

1.2 Other means of identification

Product number -
Other names 2-hydroxy-1,2-di(pyridin-2-yl)-ethan-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

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Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1141-06-6 SDS

1141-06-6Relevant articles and documents

Catalytic action of azolium salts. VI. Preparation of benzoins and acyloins by condensation of aldehydes catalyzed by azolium salts

Miyashita,Suzuki,Iwamoto,Higashino

, p. 2633 - 2635 (1994)

Benzoins 4 (2-hydroxyethanones substituted with aryl groups at the 1- and 2-positions) were prepared by self-condensation of aromatic aldehydes 3 using catalytic amounts of azolium salts 1 and 2 in excellent yields. 1,3-Dimethylbenzimidazolium iodide (2) was an effective catalyst for the preparation of acyloins 6 (2-hydroxyethanones substituted with alkyl groups at the 1- and 2-positions) by self-condensation of aliphatic aldehydes 5. On the other hand, an attempt at the condensation of hexanal (5d) catalyzed by 1,3-dimethylimidazolium iodide (1) failed to yield the acyloin 6d, and instead the aldol-type condensed product 8d was obtained.

Facile route to benzils from aldehydes via NHC-catalyzed benzoin condensation under metal-free conditions

Shimakawa, Yuuki,Morikawa, Takashi,Sakaguchi, Satoshi

, p. 1786 - 1789 (2010)

A simple and efficient one-pot procedure for the synthesis of α-diketones from aldehydes via benzoin condensation under the influence of a catalytic amount of azolium salt combined with DBU has been developed. Thus, aldehyde was allowed to react with the azolium salt/DBU catalytic system at room temperature, and then the reaction mixture was heated to 70 °C under air atmosphere to afford the corresponding 1,2-diketone in good yield. This would be an efficient alternative method of synthesizing α-diketones from aldehydes under metal-free conditions. Crown Copyright

Development of Imidazoline-2-one Derivatives as Potential Antifungal and Anthelminthic Agents: in silico and in vitro Evaluation

Chilamakuru, Naresh Babu,Mallela, Vijaya Jyothi,Peraman, Ramalingam,Shaik, Shakir Basha,Simham, Venu,Singirisetty, Triveni

, p. 423 - 433 (2021/11/24)

Based on appropriate values of synthetic accessibility concerning from ADMET properties and docking scores by docking against proteins 3OZU and 1OJ0, a series of 4,5-diphenyl-1H-imidazol-2-ones (I1?15) were synthesized. The key intermediate, 2-hydroxy-1,2-disubstitutedethanones (E1?15) were prepared by benzoin condensation using 2:1 ratio of aromatic aldehydes and thiamine in the presence of alkali. Further, these cyclized ethanones (E1?15) were treated with urea to yield 4,5-diphenyl-1H-imidazol-2-one derivatives (I1?15) and were characterized by IR,1H NMR, Mass spectra, and CHNO analysis. The synthesized compounds were screened for their anthelmintic potential on Pheretima Posthuma along with standard albendazole, and antifungal activity (minimum inhibitory concentration method) on Candida albicans and Aspergillus niger along with standard miconazole. The results revealed that among all the tested compounds I3, I4, and I7 show considerable synthetic accessibility, docking scores, anthelminthic, and antifungal activity.

One-pot synthesis of quinoxalines starting from aldehydes under metal-free conditions

Hu, Zhong-Yuan,Du, Ding,Tang, Wei-Fang,Lu, Tao

experimental part, p. 2262 - 2264 (2012/08/07)

An efficient and convenient synthesis of quinoxalines from easily available aldehydes was performed as a one-pot procedure in good to excellent yields under metal-free conditions, via sequential benzoin condensation, aerobic formation of benzils and condensation of the latter with 1,2-diaminobenzenes.

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