114152-96-4 Usage
Uses
Used in Pharmaceutical Drug Development:
Trans-2-fluorocyclopropanamine hydrochloride is used as a key intermediate in the synthesis of various pharmaceutical drugs. Its unique structure and reactivity make it a valuable component in the creation of new and innovative medications.
Used in Organic Synthesis:
As a building block in organic synthesis, Trans-2-fluorocyclopropanamine hydrochloride is used to construct a wide range of organic compounds. Its cyclopropane ring and fluorine substituent provide unique chemical properties that can be exploited in the synthesis of complex molecules.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, Trans-2-fluorocyclopropanamine hydrochloride is used as a research tool to explore the structure-activity relationships of potential drug candidates. Its incorporation into various chemical scaffolds allows researchers to investigate the effects of its unique structural features on biological activity and drug efficacy.
Used in Biological and Pharmacological Studies:
The hydrochloride salt form of Trans-2-fluorocyclopropanamine hydrochloride increases its solubility in water, making it more suitable for use in biological and pharmacological studies. This improved solubility facilitates its application in assays and experiments aimed at understanding its interactions with biological targets and evaluating its potential therapeutic effects.
Overall, Trans-2-fluorocyclopropanamine hydrochloride is a versatile chemical with a range of applications in research, drug development, and the synthesis of organic compounds. Its unique structural features and improved solubility make it a valuable asset in the field of medicinal chemistry and pharmaceutical drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 114152-96-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,1,5 and 2 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 114152-96:
(8*1)+(7*1)+(6*4)+(5*1)+(4*5)+(3*2)+(2*9)+(1*6)=94
94 % 10 = 4
So 114152-96-4 is a valid CAS Registry Number.
114152-96-4Relevant academic research and scientific papers
Synthetic studies on the key component of the new generation of quinolonecarboxylic acid, DU-6859. 1. Synthesis of (1R,2S)-2-fluorocyclopropylamine by the use of optical resolution
Tamura, Osamu,Hashimoto, Masaru,Kobayashi, Yuko,Katoh, Tadashi,Nakatani, Kazuhiko,Kamada, Masahiro,Hayakawa, Isao,Akiba, Toshifumi,Terashima, Shiro
, p. 3889 - 3904 (2007/10/02)
The title synthesis was achieved by employing highly cis-selective cyclopropanation of N-benzyl-N-vinylcarbamates with zinc-monofluorocarbenoid, deprotection of the formed N-benzyl-N-(cis-2-fluorocyclopropyl)carbamates, and optical resolution of the resul
Synthesis and optical resolution of dl-cis-2-fluorocyclopropylamine, the key component of the new generation of quinolonecarboxylic acid, DU-6859
Tamura,Hashimoto,Kobayashi,Katoh,Nakatani,Kamada,Hayakawa,Akiba,Terashima
, p. 3483 - 3486 (2007/10/02)
The title synthesis was accomplished by featuring highly cis-selective cyclopropanation of an N-vinylcarbamate with zinc-monofluorocarbenoid followed by deprotection of the formed N-(cis-2-fluorocyclopropyl)carbamate. Optical resolution of dl-cis-2-fluoro
