85679-49-8Relevant academic research and scientific papers
Enantioselective synthesis of 1-(R)-hydroxypolygodial and its 9α epimer, 1-(R)-hydroxyisotadeonal
Della Monica, Carmela,Della Sala, Giorgio,Izzo, Irene,De Petrocellis, Luciano,di Marzo, Vincenzo,Spinella, Aldo
, p. 6866 - 6873 (2008/02/07)
The enantioselective synthesis of 1-(R)-hydroxypolygodial and its epimer at C-9 is described. α-Ionone was the starting material. Key steps of these syntheses included a Corey-Bakshi-Shibata oxazaborolidine-mediated reduction and a stereoselective Diels-A
Enantioselective synthesis of 1(R)-hydroxypolygodial
Della Monica, Carmela,Della Sala, Giorgio,D'Urso, Deborah,Izzo, Irene,Spinella, Aldo
, p. 4061 - 4063 (2007/10/03)
Enantioselective preparation of 1(R)-hydroxypolygodial (5) has been achieved starting from α-ionone through a synthetic strategy involving a Corey-Bakshi-Shibata oxazaborolidine-mediated reduction and a stereoselective Diels-Alder reaction as key steps.
Total synthesis of forskolin - Part I
Delpech, Bernard,Calvo, Daniel,Lett, Robert
, p. 1015 - 1018 (2007/10/03)
A new total synthesis of forskolin 1 has been achieved and this note describes the synthesis of the transfused enone 18 as a key-intermediate. Key steps are: 1) the intramolecular Diels-Alder reaction of 17 to afford the tricyclic lactone 8 (48-56%); 2) a
A New Acetylene Rearrangement
Leapheart, Theophilus,Magnus, Philip
, p. 1391 - 1392 (2007/10/02)
Treatment of the enynols (1), (2), (3), and (5) with 35percent perchloric acid in tetrahydrofuran produces, through a series of prototropic shifts, the corresponding dienones (4) and (11).
