114443-84-4

Upstream product

• 3360-72-3 (anilino-pyridin-4-yl-methyl)-phosphonic acid diphenyl ester 
• 100-52-7 benzaldehyde 
• 27768-46-3 N-(pyridin-4-ylmethylene)aniline 
• 62-53-3 aniline 
• 872-85-5 pyridine-4-carbaldehyde 

Downstream Products

• 1017-24-9 2-phenyl-1-pyridin-4-yl-ethanone 
• 114443-53-7 1-Methyl-4-phenylacetyl-pyridinium; bromide 
• 100240-06-0 4-(phenylacetyl)pyridinium chloride 

Relevant academic research and scientific papers

An improved and practical procedure for the synthesis of substituted phenylacetylpyridines

A general procedure for the synthesis of substituted phenylacetylpyridines in excellent yields is described using a Horner-Emmons condensation between α-aminoalkylphosphonates of pyridinecarboxaldehydes and benzaldehydes with cesium carbonate at room temperature.

Equilibrium and Kinetic Acidities of Benzylic Ketones. Application of the Marcus Equation to the Deprotonation of Carbon Acids

Equilibrium constants and rates of ketone-enolate ion equilibration have been measured for the deprotonation of eight 3-(X-phenylacetyl)pyridines 1 (pKa 13.2 for X = H), ten 4-(X-phenylacetyl)pyridines 2 (pKa 12.2 for X = H), nine 1-