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114494-94-9

(E)-5-(2-bromovinyl)-2'-deoxy-5'-O-t-butyldiphenylsilyluridine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 114494-94-9 Structure

  • Basic information

    1. Product Name: (E)-5-(2-bromovinyl)-2'-deoxy-5'-O-t-butyldiphenylsilyluridine
    2. Synonyms: (E)-5-(2-bromovinyl)-2'-deoxy-5'-O-t-butyldiphenylsilyluridine
    3. CAS NO:114494-94-9
    4. Molecular Formula:
    5. Molecular Weight: 571.543
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 114494-94-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (E)-5-(2-bromovinyl)-2'-deoxy-5'-O-t-butyldiphenylsilyluridine(CAS DataBase Reference)
    10. NIST Chemistry Reference: (E)-5-(2-bromovinyl)-2'-deoxy-5'-O-t-butyldiphenylsilyluridine(114494-94-9)
    11. EPA Substance Registry System: (E)-5-(2-bromovinyl)-2'-deoxy-5'-O-t-butyldiphenylsilyluridine(114494-94-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 114494-94-9(Hazardous Substances Data)

114494-94-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 114494-94-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,4,9 and 4 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 114494-94:
(8*1)+(7*1)+(6*4)+(5*4)+(4*9)+(3*4)+(2*9)+(1*4)=129
129 % 10 = 9
So 114494-94-9 is a valid CAS Registry Number.

114494-94-9Relevant articles and documents

THE SYNTHESIS AND ANTIVIRAL PROPERTIES OF (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE-RELATED COMPOUNDS

Ashwell, Mark,Jones, A. Stanley,Kumar, Ajit,Sayers, Jon R.,Walker, Richard T.,et. al.

, p. 4601 - 4608 (2007/10/02)

A method for the synthesis of the potent anti-herpes agent, (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) (1) is described.A trace bye-product of the synthesis has been identified as 5-(1,2-dibromo-2-succinimidoethyl)-2'-deoxyuridine (5).A similar bye-product, 5-(1,2-dibromo-2-succinimidoethyl)uridine (4) is formed during the synthesis of (E)-5-(2-bromovinyl)uridine (3).The following derivatives of BVDU have been synthesised: 3'-O-methyl (8), 3-methyl (9), 4-O-ethyl (11), O2,5'-anhydro-(E)-5-(2-bromovinyl)-2'-deoxyuridine (13) and (E)-5-(2-bromovinyl)-2'-deoxyisocytidine (15).Whereas compounds 8, 9 and 15 showed little, if any, antiviral activity, 11 and, in particular, 13, were significantly active against herpes simplex virus type 1 and varicella-zoster virus.

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