114503-42-3

Usage

Uses

Used in Organic Synthesis:
2,5-dimethoxyterephthalohydrazide is used as a reagent in organic synthesis for the preparation of azo dyes and polyester resins. Its unique chemical structure allows it to act as an intermediate in the formation of these compounds, contributing to the development of a wide range of products.
Used in Dye Industry:
In the dye industry, 2,5-dimethoxyterephthalohydrazide is used as a key component in the production of azo dyes. These dyes are known for their colorfastness and are widely used in various applications, including textiles, plastics, and printing inks.
Used in Polymer Industry:
2,5-dimethoxyterephthalohydrazide is used as a monomer in the synthesis of polyester resins. These resins are valued for their durability, heat resistance, and chemical stability, making them suitable for use in coatings, adhesives, and composite materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,5-dimethoxyterephthalohydrazide is used in the production of dye intermediates, which are essential for the synthesis of various drugs. Its versatility in chemical reactions enables the development of a broad spectrum of pharmaceutical compounds.
Used in Agrochemical Industry:
2,5-dimethoxyterephthalohydrazide is also utilized in the agrochemical industry for the synthesis of active ingredients in pesticides and other agricultural chemicals. Its role in these applications contributes to the development of effective solutions for crop protection and management.
Used in Corrosion Inhibition:
2,5-dimethoxyterephthalohydrazide has been investigated for its potential use as a corrosion inhibitor in metal surfaces. Its ability to form protective layers on metal surfaces can help prevent corrosion, extending the lifespan of various metal components and structures.

Upstream product

• 2674-34-2 1,4-dibromo-2,5-dimethoxybenzene 
• 173267-23-7 diethyl-2,5-dimethoxy-1,4-benzenedicarboxylate 
• 150-78-7 1,4-dimethoxybezene 
• 21004-12-6 2,5-dimethoxyterephthalic acid dimethyl ester 
• 610-92-4 2,5-dihydroxy-1,4-benzenedicarboxylic acid 

Relevant academic research and scientific papers

Covalent organic frameworks as pH responsive signaling scaffolds

A β-ketoenamine based covalent organic framework, COF-JLU4, was synthesized by condensation of 2,5-dimethoxyterephthalohydrazide with triformylphloroglucinol under solvothermal conditions. This COF has strong crystallinity, good porosity, photoluminescence properties and wettability for water. It can serve as the first COF-based fluorescent pH sensor in aqueous solutions.

Linkage Engineering by Harnessing Supramolecular Interactions to Fabricate 2D Hydrazone-Linked Covalent Organic Framework Platforms toward Advanced Catalysis

Covalent organic frameworks (COFs) are an emerging class of crystalline porous polymers with tailor-made structures and functionalities. To facilitate their utilization for advanced applications, it is crucial to develop a systematic approach to control the properties of COFs, including the crystallinity, stability, and functionalities. However, such an integrated design is challenging to achieve. Herein, we report supramolecular strategy-based linkage engineering to fabricate a versatile 2D hydrazone-linked COF platform for the coordination of different transition metal ions. Intra- and intermolecular hydrogen bonding as well as electrostatic interactions in the antiparallel stacking mode were first utilized to obtain two isoreticular COFs, namely COF-DB and COF-DT. On account of suitable nitrogen sites in COF-DB, the further metalation of COF-DB was accomplished upon the complexation with seven divalent transition metal ions M(II) (M = Mn, Co, Ni, Cu, Zn, Pd, and Cd) under mild conditions. The resultant M/COF-DB exhibited extended π-conjugation, improved crystallinity, enhanced stability, and additional functionalities as compared to the parent COF-DB. Furthermore, the dynamic nature of the coordination bonding in M/COF-DB allows for the easy replacement of metal ions through a postsynthetic exchange. In particular, the coordination mode in Pd/COF-DB endows it with excellent catalytic activity and cyclic stability as a heterogeneous catalyst for the Suzuki-Miyaura cross-coupling reaction, outperforming its amorphous counterparts and Pd/COF-DT. This strategy provides an opportunity for the construction of 2D COFs with designable functions and opens an avenue to create COFs as multifunctional systems.

Robust covalent organic frameworks with tailor-made chelating sites for synergistic capture of U(vi) ions from highly acidic radioactive waste

A synergistic strategy for enhancing U(vi) capture under highly acidic conditions (2 M HNO3) by radiation resistant phosphonate-functionalized two-dimensional covalent organic frameworks with tailor-made binding sites bearing a strong affinity was described. The combination of the radiation resistant characteristic with a strong acid-resistant property endows COFs with practical capabilities for actinide capture from real radioactive liquid waste.

Covalent Organic Frameworks toward Diverse Photocatalytic Aerobic Oxidations

Photoactive two-dimensional covalent organic frameworks (2D-COFs) have become promising heterogenous photocatalysts in visible-light-driven organic transformations. Herein, a visible-light-driven selective aerobic oxidation of various small organic molecules by using 2D-COFs as the photocatalyst was developed. In this protocol, due to the remarkable photocatalytic capability of hydrazone-based 2D-COF-1 on molecular oxygen activation, a wide range of amides, quinolones, heterocyclic compounds, and sulfoxides were obtained with high efficiency and excellent functional group tolerance under very mild reaction conditions. Furthermore, benefiting from the inherent advantage of heterogenous photocatalysis, prominent sustainability and easy photocatalyst recyclability, a drug molecule (modafinil) and an oxidized mustard gas simulant (2-chloroethyl ethyl sulfoxide) were selectively and easily obtained in scale-up reactions. Mechanistic investigations were conducted using radical quenching experiments and in situ ESR spectroscopy, all corroborating the proposed role of 2D-COF-1 in photocatalytic cycle.