114523-69-2

Usage

Uses

Used in Pharmaceutical Synthesis:
1(2H)-Pyridinecarboxylic acid, 5,6-dihydro-2-methoxy-, methyl ester is used as a building block for the synthesis of various pharmaceuticals. Its unique structure allows for the creation of a wide range of drug candidates, contributing to the development of new treatments for various medical conditions.
Used in Agrochemical Production:
In the agrochemical industry, 1(2H)-Pyridinecarboxylic acid, 5,6-dihydro-2-methoxy-, methyl ester is used as an intermediate in the synthesis of herbicides and insecticides. Its incorporation into these products enhances their effectiveness in controlling pests and unwanted plant growth, supporting agricultural productivity.
Used in Novel Material Development:
1(2H)-Pyridinecarboxylic acid, 5,6-dihydro-2-methoxy-, methyl ester also has potential applications in the development of novel materials, thanks to its unique chemical properties. Researchers can leverage its characteristics to create innovative materials with specific properties for various industrial applications.
Used as a Reagent in Organic Synthesis:
1(2H)-Pyridinecarboxylic acid, 5,6-dihydro-2-methoxy-, methyl ester is utilized as a reagent in organic synthesis, facilitating various chemical reactions and contributing to the production of a diverse array of organic compounds for different industries.

Upstream product

• 56475-87-7 3,4-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 124-41-4 sodium methylate 
• 56475-86-6 2-methoxy-piperidine-1-carboxylic acid methyl ester 
• 1796-27-6 piperidine-1-carboxylic acid methyl ester 
• 113718-34-6 β-bromo-α-methoxy-N-(methoxycarbonyl)piperidine 

Downstream Products

• 125593-06-8 1-(methoxycarbonyl)-2-phenyl-1,2,5,6-tetrahydropyridine 
• 131667-51-1 1-(methoxycarbonyl)-4-phenyl-1,2,3,4-tetrahydropyridine 
• 33707-36-7 1-(methoxycarbonyl)-1,2-dihydropyridine 

Relevant academic research and scientific papers

A NEW METHOD FOR REGIOSELECTIVE SYNTHESIS OF 2-SUBSTITUTED 1-(METHOXYCARBONYL)-1,2-DIHYDROPYRIDINES

2-Substituted 1,2-dihydropyridines including an optically active one were regioselctively prepared from 2-substituted piperidines through three intermediates, that is, (a) 1,2,3,4-tetrahydropyridines, (b) 5-bromo-6-methoxypiperidines, and (c) 1,2,3,4-tetrahydro-6-methoxypyridines.

Stereoselective synthesis of 3-deoxy-piperidine iminosugars from l-lysine

A new method using electrochemical oxidation and/or OsO4 oxidation has been used for the stereoselective synthesis of 2,3,6-trihydroxylated (5S)-piperidine derivatives. The electrochemical method was successively used for the conversion of N-pr

Stereoselective synthesis of azasugars by electrochemical oxidation

A new method using electrochemical oxidation has been exploited for the stereoselective synthesis of 2,3,6-trihydroxylated 5S-piperidine derivatives. The electrochemical method was successively used for the conversion of N-protected piperidines to N-prote

A convenient method for synthesis of optically active methylphenidate from N-methoxycarbonylpiperidine by utilizing electrochemical oxidation and Evans aldol-type reaction

A new method to prepare optically active methylphenidate starting from piperidine is described. The method consists of a transformation of N-methoxycarbonylated piperidine to the corresponding α-methoxylated carbamate utilizing electrochemical oxidation f

REGIOSELECTIVE INTRODUCTION OF ALKYL GROUPS TO THE POSITION α OR γ TO NITROGEN ATOM OF PIPERIDINE SKELETONS USING ANODIC OXIDATION IN A KEY STEP

β,γ-Unsaturated N-alkoxycarbonyl-α-methoxypiperidines, which were prepared from N-alkoxypiperidines by using anodic oxidation in a key step, were regioselectively alkylated at the α-position by using Grignard reagents in the presence of BF3*Et2O, whereas in the presence of CuBr, the alkylation took place at the γ-position.