A NEW METHOD FOR REGIOSELECTIVE SYNTHESIS OF 2-SUBSTITUTED 1-(METHOXYCARBONYL)-1,2-DIHYDROPYRIDINES

Article abstract of DOI:10.1016/S0040-4039(01)83864-8

2-Substituted 1,2-dihydropyridines including an optically active one were regioselctively prepared from 2-substituted piperidines through three intermediates, that is, (a) 1,2,3,4-tetrahydropyridines, (b) 5-bromo-6-methoxypiperidines, and (c) 1,2,3,4-tetrahydro-6-methoxypyridines.