114531-88-3

Upstream product

• 712-50-5 Cyclohexyl phenyl ketone 
• 105-36-2 ethyl bromoacetate 
• 26482-37-1 (+/-)-3-cyclohexyl-3-hydroxy-3-phenylpropanoic acid ethyl ester 
• 78620-93-6 (+/-)-3-cyclohexyl-3-hydroxy-3-phenylpropanoic acid 

Downstream Products

• 149597-98-8 (R)-(-)-1-cyclohexyl-1-phenyl-1,3-propanediol 
• 149714-37-4 (2R,3R)-(-)-3-cyclohexyl-2,3-epoxy-3-phenylpropyl 4-nitrobenzenesulfonate 
• 149714-36-3 (2S,3R)-(-)-3-cyclohexyl-2,3-epoxy-3-phenylpropyl 4-nitrobenzenesulfonate 
• 149598-00-5 (R)-(-)-3-cyclohexyl-3-hydroxy-3-phenylpropyl 4-nitrobenzenesulfonate 
• 149598-03-8 (1R,2R)-(-)-1-cyclohexyl-2,3-epoxy-1-phenyl-1-propanol 
• 149598-02-7 (1R,2S)-(-)-1-cyclohexyl-2,3-epoxy-1-phenyl-1-propanol 
• 149714-33-0 (+)-(2R,3R)-trans-3-cyclohexyl-3-phenyloxiranemethanol 
• 149714-34-1 (2S,3R)-(-)-3-cyclohexyl-2,3-epoxy-3-phenyl-1-propanol 
• 149714-31-8 (R)-(-)-1-cyclohexyl-1-phenyl-2-propen-1-ol 

Relevant academic research and scientific papers

Anticholinergic Agents 3. Synthesis and Configurational Assignment of the Four Stereoisomers of 1-Cyclohexyl-1,2-epoxy-1-phenyl-3-piperidinylpropane

The four stereoisomers of 1-cyclohexyl-1,2-epoxy-1-phenyl-3-piperidylpropane which are putative muscarinic antagonists, have been synthesised employing (S)- and (R)-1-cyclohexyl-1-phenyl-1,3-propanediol as chiral synthons.The relative configuration of the

Syntheses of (S)-(+)-trihexyphenidyl hydrochloride and (S)-(+)-procyclidine hydrochloride, two anticholinergics, using (S)-(-)-3-cyclohexyl-3-hydroxy-3-phenylpropanoic acid as chiral synthon.

The absolute configuration of the more active (-)-enantiomer of the anticholinergic trihexyphenidyl hydrochloride has been established as (R) by syntheses of (S)-(+)-procyclidine hydrochloride, whose absolute configuration has been established previously,