78620-93-6Relevant academic research and scientific papers
Ultrasound in enzymatic resolution of ethyl 3-hydroxy-3-phenylpropanoate
Ribeiro, Carlos Magno R.,Passaroto, Elisa N.,Brenelli, Eugênia C.S.
, p. 6477 - 6479 (2007/10/03)
The enzymatic hydrolysis of ethyl-3-hydroxy-3-phenylpropanoate using ultrasound bath and PCL, PLE and CRL enzymes was studied. The application of ultrasound bath led to an appreciative decrease in the reaction time of enzymatic hydrolysis without a signif
Anticholinergic Agents 3. Synthesis and Configurational Assignment of the Four Stereoisomers of 1-Cyclohexyl-1,2-epoxy-1-phenyl-3-piperidinylpropane
Sjoe, Peter,Aasen, Arne Joergen
, p. 486 - 491 (2007/10/02)
The four stereoisomers of 1-cyclohexyl-1,2-epoxy-1-phenyl-3-piperidylpropane which are putative muscarinic antagonists, have been synthesised employing (S)- and (R)-1-cyclohexyl-1-phenyl-1,3-propanediol as chiral synthons.The relative configuration of the
Syntheses of (S)-(+)-trihexyphenidyl hydrochloride and (S)-(+)-procyclidine hydrochloride, two anticholinergics, using (S)-(-)-3-cyclohexyl-3-hydroxy-3-phenylpropanoic acid as chiral synthon.
Schjelderup,Harbitz,Groth,Aasen
, p. 356 - 361 (2007/10/02)
The absolute configuration of the more active (-)-enantiomer of the anticholinergic trihexyphenidyl hydrochloride has been established as (R) by syntheses of (S)-(+)-procyclidine hydrochloride, whose absolute configuration has been established previously,
