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1145681-01-1

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1145681-01-1 Usage

Structure

Cyclobutane carboxylic acid derivative with a hydroxyl group and a chlorophenyl group attached to the cyclobutane ring

Potential applications

Pharmaceutical properties and applications in medicinal chemistry

Synthesis

Can be used as a starting material for the synthesis of other compounds with therapeutic potential

Biological activities

May have potential pharmacological effects and could be studied for its biological activities

Research tool

Can be used in the study of cyclobutane carboxylic acids and their role in drug development

Check Digit Verification of cas no

The CAS Registry Mumber 1145681-01-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,5,6,8 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1145681-01:
(9*1)+(8*1)+(7*4)+(6*5)+(5*6)+(4*8)+(3*1)+(2*0)+(1*1)=141
141 % 10 = 1
So 1145681-01-1 is a valid CAS Registry Number.

1145681-01-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-chlorophenyl)-3-hydroxycyclobutane-1-carboxylic acid

1.2 Other means of identification

Product number -
Other names I04-1313

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1145681-01-1 SDS

1145681-01-1Relevant articles and documents

Convergent, kilogram scale synthesis of an Akt kinase inhibitor

Grongsaard, Pintipa,Bulger, Paul G.,Wallace, Debra J.,Tan, Lushi,Chen, Qinghao,Dolman, Sarah J.,Nyrop, Jason,Hoerrner, R. Scott,Weisel, Mark,Arredondo, Juan,Itoh, Takahiro,Xie, Chengfu,Wen, Xianghui,Zhao, Dalian,Muzzio, Daniel J.,Bassan, Ephraim M.,Shultz, C. Scott

supporting information; experimental part, p. 1069 - 1081 (2012/08/27)

The development of a convergent, chromatography-free synthesis of an allosteric Akt kinase inhibitor is described. The route comprised 17 total steps and was used to produce kilogram quantities of the target molecule. A key early transformation, for which

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