1145681-01-1 Usage
Structure
Cyclobutane carboxylic acid derivative with a hydroxyl group and a chlorophenyl group attached to the cyclobutane ring
Potential applications
Pharmaceutical properties and applications in medicinal chemistry
Synthesis
Can be used as a starting material for the synthesis of other compounds with therapeutic potential
Biological activities
May have potential pharmacological effects and could be studied for its biological activities
Research tool
Can be used in the study of cyclobutane carboxylic acids and their role in drug development
Check Digit Verification of cas no
The CAS Registry Mumber 1145681-01-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,5,6,8 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1145681-01:
(9*1)+(8*1)+(7*4)+(6*5)+(5*6)+(4*8)+(3*1)+(2*0)+(1*1)=141
141 % 10 = 1
So 1145681-01-1 is a valid CAS Registry Number.
1145681-01-1Relevant articles and documents
Convergent, kilogram scale synthesis of an Akt kinase inhibitor
Grongsaard, Pintipa,Bulger, Paul G.,Wallace, Debra J.,Tan, Lushi,Chen, Qinghao,Dolman, Sarah J.,Nyrop, Jason,Hoerrner, R. Scott,Weisel, Mark,Arredondo, Juan,Itoh, Takahiro,Xie, Chengfu,Wen, Xianghui,Zhao, Dalian,Muzzio, Daniel J.,Bassan, Ephraim M.,Shultz, C. Scott
supporting information; experimental part, p. 1069 - 1081 (2012/08/27)
The development of a convergent, chromatography-free synthesis of an allosteric Akt kinase inhibitor is described. The route comprised 17 total steps and was used to produce kilogram quantities of the target molecule. A key early transformation, for which