114628-27-2Relevant academic research and scientific papers
Electrophilic Olefin Heterocyclization in Organic Synthesis. Highly Stereoselective Synthesis of Trans 3,5-Disubstituted Pyrrolidin-2-ones by Iodolactamization via Homoallylic Asymmetric Induction
Takahata, Hiroki,Takamatsu, Tamotsu,Chen, Yin-Shan,Ohkubo, Naoki,Yamazaki, Takao,et al.
, p. 3792 - 3797 (2007/10/02)
α-Substituted γ,δ-unsaturated thioimidates 19-24, prepared by methylation of the corresponding thioamides 13-18, undergo iodine-induced lactamization to provide the 3,5-disubstituted pyrrolidin-2-ones 25a,b-30a,b.High 1,3-asymmetric induction by the homoa
Highly Selective Iodine-Induced Lactam Formation from γ,δ-Unsaturated Thioimidates. New Entry to Functionalized γ-Lactams
Takahata, Hiroki,Takamatsu, Tamotsu,Mozumi, Mayumi,Chen, Yin-Shan,Yamazaki, Takao,Aoe, Keiichi
, p. 1627 - 1629 (2007/10/02)
Iodine-induced lactam formation from γ,δ-unsaturated thioimidates proceeds regio- and stereoselectively, providing highly functionalized γ-lactams.
