114691-92-8Relevant articles and documents
Ligand-free palladium catalysis of the Suzuki reaction in water using microwave heating
Leadbeater, Nicholas E.,Marco, Maria
, p. 2973 - 2976 (2002)
(figure presented) We report the ligand-free palladium catalysis of the Suzuki reaction in water using microwave heating. Our methodology uses low palladium loadings (0.4 mol %), is fast (5-10 min reaction time), and is useful for couplings involving boronic acids and aryl iodides, bromides, and chlorides.
A liquid-phase approach to functionalized janus dendrimers: Novel soluble supports for organic synthesis
Feng, Yu,He, Yan-Mei,Zhao, Li-Wen,Huang, Yi-Yong,Fan, Qing-Hua
, p. 2261 - 2264 (2007)
A new kind of functionalized Janus dendrimer has been synthesized via a liquid-phase approach, which could easily be purified using a simple precipitation method without the need for chromatographic separation. Their use for liquid-phase organic synthesis has been achieved in the Pd-catalyzed Suzuki coupling reactions, giving biaryl products in excellent yields after cleavage.
A general approach to N-heterocyclic carbenes with a fused tetracyclic core: Ligands for suzuki-miyaura cross-coupling reaction
Sutar, Revannath L.,Kumar, Vinod,Shingare, Rahul D.,Thorat, Shridhar,Gonnade, Rajesh,Reddy, D. Srinivasa
, p. 4482 - 4486 (2014)
The synthesis of an N-heterocyclic carbene (NHC) based on a tetracyclic scaffold by using simple, general, and scalable chemistry is disclosed. The developed route is suitable for introducing multiple substitutions on the tetracyclic scaffold. The utility of the present NHC as a ligand in the Suzuki-Miyaura cross-coupling reaction is demonstrated with a low catalyst loading. Copyright
Synthesis of water soluble Pd-Piperidoimidazolin-2-ylidene complexes and their catalytic activities in neat water
?ak?r, Sinem,Türkmen, Hayati
, (2020/02/04)
Through the strategy of water soluble N-heterocyclic carbene (NHC) ligand, Pd-catalyzed reactions were developed in aqueous media. Therefore, four new piperidoimidazolinium salts (1a-d) consisting of sulfonate (a), esther (b, c) and carboxylic acid (d) functionalities and their water-soluble Pd-NHC complexes (2a-d) were synthesized. The new compounds were characterized by elemental analysis, FTIR, TGA, UV–vis and NMR spectroscopy. The catalytic activities of water soluble Pd-NHC complexes (2a-d) were investigated using the Suzuki-Miyaura (S-M) reaction and the reduction of nitroarenes. We found that the water-soluble polar or ionic groups on piperidoimidazolin-2-ylidine had an effect on the catalytic activity. The water-soluble catalyst can be recycled efficiently and reused six times with only a very slight loss of catalytic activity.