1146975-16-7

Upstream product

• 185331-69-5 1-bromo-2-fluoro-4-nitrobenzene 
• 188975-47-5 dimethyl 2-(2-fluoro-4-nitrophenyl)malonate 
• 1146975-15-6 Trimethyl 1-(2-fluoro-4-nitrophenyl)propane-1,1,3-tricarboxylate 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 1146975-17-8 4-(2-Fluoro-4-nitrophenyl)butanoic acid 
• 1398048-60-6 2-(3-(2-fluoro-4-nitrophenyl)propyl)-4,5-dihydro-1H-imidazole 
• 1398048-62-8 2-(3-(2-fluoro-4-nitrophenyl)propyl)-1H-imidazole 
• 1146975-19-0 4-(4-Amino-2-fluorophenyl)-N-methylbutanamide 
• 1146975-20-3 4-(4-(1-Cyanocyclobutylamino)-2-fluorophenyl)-N-methylbutanamide 
• 1384959-94-7 C₁₁H₁₄FNO₂ 
• 1398048-06-0 C₁₅H₂₀FN₃O 
• 1398045-83-4 4-{4-[3-(4-cyano-2-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-2-fluoro-phenyl}-N-methyl-butyramide 
• 1398045-87-8 4-{4-[7-(4-cyano-2-fluoro-3-trifluoromethyl-phenyl)-8-oxo-6-thioxo-5,7-diaza-spiro[3.4]oct-5-yl]-2-fluoro-phenyl}-N-methyl-butyramide 
• 1398048-19-5 C₁₀H₁₁FN₂O₃ 
• 1398048-21-9 C₁₂H₁₁FN₂O₃ 
• 1398048-23-1 C₁₂H₁₃FN₂O 
• 1398048-25-3 C₁₆H₁₈FN₃O 
• 1398045-93-6 3-fluoro-4-{3-[3-fluoro-4-(3-oxazol-2-yl-propyl)-phenyl]-4,4-dimethyl-5-oxo-2-thioxo-imidazolidin-1-yl}-2-trifluoromethyl-benzonitrile 

Relevant academic research and scientific papers

ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF

Disclosed are substituted thioimidazolidinone compounds and pharmaceutical compositions comprising such compounds. The compounds and compositions can be used for treatment of androgen receptor-associated diseases or disorders, such as prostate cancer, benign prostatic hypertrophy, male hair loss and hypertrichosis.

DIARYLHYDANTOIN COMPOUNDS

The present invention relates to diarylhydantoin compounds and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.