188975-47-5

Basic information

• Product Name: DiMethyl 2-(2-Fluoro-4-nitrophenyl)Malonate
• Synonyms: DiMethyl 2-(2-Fluoro-4-nitrophenyl)Malonate;2-(2-fluoro-4-nitrophenyl)Propanedioic acid 1,3-dimethyl ester
• CAS NO: 188975-47-5
• Molecular Formula: C₁₁H₁₀FNO₆
• Molecular Weight: 271.1986032
• Mol File: 188975-47-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: DiMethyl 2-(2-Fluoro-4-nitrophenyl)Malonate(CAS DataBase Reference)
• NIST Chemistry Reference: DiMethyl 2-(2-Fluoro-4-nitrophenyl)Malonate(188975-47-5)
• EPA Substance Registry System: DiMethyl 2-(2-Fluoro-4-nitrophenyl)Malonate(188975-47-5)

Safety Data

• Hazardous Substances Data: 188975-47-5(Hazardous Substances Data)

Usage

General Description

DiMethyl 2-(2-Fluoro-4-nitrophenyl)Malonate is a chemical compound commonly used in organic synthesis and pharmaceutical research. It is a malonic ester derivative containing two methyl groups and a 2-(2-fluoro-4-nitrophenyl) group. DiMethyl 2-(2-Fluoro-4-nitrophenyl)Malonate is often employed as a building block for the synthesis of various biologically active molecules and is also used as a starting material for the production of agrochemicals and pharmaceuticals. Its unique structure and reactivity make it a valuable tool for the development of new drugs and materials. Additionally, it has shown potential as a fluorescent probe for detecting biological molecules and has been studied for its potential antimicrobial and anticancer properties.

Upstream product

• 108-59-8 malonic acid dimethyl ester 
• 185331-69-5 1-bromo-2-fluoro-4-nitrobenzene 
• 369-34-6 3,4-difluoronitrobenzene 

Downstream Products

• 337529-74-5 methyl 2-(4-nitro-2-fluorophenyl)acetate 
• 1160623-38-0 ethyl 2-(2-fluoro-4-nitrophenyl)acetate 
• 1146975-25-8 Dimethyl 2-(2-cyanoethyl)-2-(2-fluoro-4-nitrophenyl)malonate 
• 1398047-64-7 methyl 4-cyano-2-(2-fluoro-4-nitrophenyl)butanoate 
• 1146975-15-6 Trimethyl 1-(2-fluoro-4-nitrophenyl)propane-1,1,3-tricarboxylate 
• 1146975-24-7 dimethyl 2-(2-fluoro-4-nitrophenyl)pentanedioate 
• 1146975-36-1 4-(4-((2-cyanopropan-2-yl)amino)-2-fluorophenyl)butanenitrile 
• 1146975-16-7 Methyl 4-(2-fluoro-4-nitrophenyl)butanoate 
• 1146975-17-8 4-(2-Fluoro-4-nitrophenyl)butanoic acid 
• 1146975-19-0 4-(4-Amino-2-fluorophenyl)-N-methylbutanamide 
• 1146975-20-3 4-(4-(1-Cyanocyclobutylamino)-2-fluorophenyl)-N-methylbutanamide 
• 1146975-26-9 4-(2-Fluoro-4-nitrophenyl)butanenitrile 
• 1146975-27-0 4-(4-Amino-2-fluorophenyl)butanenitrile 
• 1146975-28-1 4-(4-((2-cyanopropan-2-yl)amino)-2-fluorophenyl)butanenitrile 

Relevant articles and documents

SUBSTITUTED PYRAZOLYL-BASED CARBOXAMIDE AND UREA DERIVATIVES BEARING A PHENYL MOIETY SUBSTITUTED WITH AN O-CONTAINING GROUP AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted pyrazolyl-based carboxamide and urea derivatives of formula (Q) as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

DIARYLHYDANTOIN COMPOUNDS

The present invention relates to diarylhydantoin compounds and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.

SUBSTITUTED PHENYLAMINO-PYRIMIDINES

The invention relates to substituted phenylamino-pyrimidines, to a method for their production and to their use for producing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular for the treatment of cardiovascular diseases.