1146975-19-0

Upstream product

• 1146975-16-7 Methyl 4-(2-fluoro-4-nitrophenyl)butanoate 
• 185331-69-5 1-bromo-2-fluoro-4-nitrobenzene 
• 188975-47-5 dimethyl 2-(2-fluoro-4-nitrophenyl)malonate 
• 1384959-94-7 C₁₁H₁₄FNO₂ 
• 74-89-5 methylamine 
• 1146975-18-9 4-(2-Fluoro-4-nitrophenyl)-N-methylbutanamide 

Downstream Products

• 1146975-20-3 4-(4-(1-Cyanocyclobutylamino)-2-fluorophenyl)-N-methylbutanamide 
• 1398045-83-4 4-{4-[3-(4-cyano-2-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-2-fluoro-phenyl}-N-methyl-butyramide 
• 1398048-06-0 C₁₅H₂₀FN₃O 

Relevant academic research and scientific papers

Sulfo-imidazole diketone androgen receptor antagonist and applications thereof

The invention discloses a sulfo-imidazole diketone compound represented by the formula (I). The sulfo-imidazole diketone compound can be used as an androgen receptor and can be used to prepare drugs for treating diseases or disorders related with androgen receptors such as cancer, and the like.

ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF

Disclosed are substituted thioimidazolidinone compounds and pharmaceutical compositions comprising such compounds. The compounds and compositions can be used for treatment of androgen receptor-associated diseases or disorders, such as prostate cancer, benign prostatic hypertrophy, male hair loss and hypertrichosis.

DIARYLHYDANTOIN COMPOUNDS

The present invention relates to diarylhydantoin compounds and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.