1147-25-7Relevant articles and documents
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Murray et al.
, p. 4901,4905 (1971)
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Ermatov et al.
, (1968)
Synthesis of coumarin derivatives and their cytoprotective effects on t-BHP-induced oxidative damage in HepG2 cells
Ando, Tomomi,Nagumo, Mina,Ninomiya, Masayuki,Tanaka, Kaori,Linhardt, Robert J.,Koketsu, Mamoru
supporting information, p. 2422 - 2425 (2018/06/20)
Coumarins are ubiquitous in higher plants and exhibit various biological actions. The aim of this study was to investigate the structure-activity relationships of coumarin derivatives on tert-butyl hydroperoxide (t-BHP)-induced oxidative damage in human hepatoma HepG2 cells. A series of coumarin derivatives were prepared and assessed for their cytoprotective effects. Among these, a caffeoyl acid-conjugated dihydropyranocoumarin derivative, caffeoyllomatin, efficiently protected against cell damage elicited by t-BHP. Our findings suggest that caffeoyllomatin appears to be a potent cytoprotective agent.
SYNTHESIS, GLYCOSIDATION AND RESOLUTION OF (+/-)-LOMATIN
Skaltsounis, Alexios-Leandros,Mitaku, Sofia,Gaudel, Gilbert,Tillequin, Francois,Koch, Michel
, p. 121 - 128 (2007/10/02)
The first resolution of a racemic hydroxydihydropyranocoumarin, (+/-)-lomatin (1) was achieved by means of glycosidation, followed by separation of the diastereoisomeric glycosides and subsequent acid hydrolysis.