114710-69-9Relevant academic research and scientific papers
Heterocyclization of N-hetaryl-N′-(prop-2-en-1-yl)thioureas by the action of sulfuryl chloride
Zborovskii,Orysyk,Staninets,Rusanov,Chernega
, p. 1030 - 1034 (2007)
Cyclization of N-hetaryl-N′-(prop-2-en-1-yl)thioureas by the action of sulfuryl chloride leads to the formation of the corresponding 2-hetarylimino-5-chloromethylthiazolidine hydrochlorides which are converted into the free bases by treatment with aqueous
Influence of Substituents on the Synthesis of Thiazolidinones
Sabu, M.,Garnaik, B. K.,Behera, Rajani K.
, p. 779 - 781 (2007/10/02)
The influence of substituents (subunits) in the synthesis of thiazolidinones by the reaction of unsymmetrical thioureas with monochloroacetic acid in ethanol has been rationalised by the characterisation of the hydrolysis products of the resulting thiazolidinones.The formation of thiol from thiourea, which is the key intermediate in thiazolidinone synthesis, invariably involves the -NH- group adjacent to more electron withdrawing subunits.
