114716-44-8

Basic information

• Product Name: (1R^*,2R^*)-(Z)-4-chloro-2-methyl-1-phenyl-3-buten-1-ol
• Synonyms: (1R^*,2R^*)-(Z)-4-chloro-2-methyl-1-phenyl-3-buten-1-ol
• CAS NO: 114716-44-8
• Molecular Weight: 196.677
• Mol File: 114716-44-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1R^*,2R^*)-(Z)-4-chloro-2-methyl-1-phenyl-3-buten-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R^*,2R^*)-(Z)-4-chloro-2-methyl-1-phenyl-3-buten-1-ol(114716-44-8)
• EPA Substance Registry System: (1R^*,2R^*)-(Z)-4-chloro-2-methyl-1-phenyl-3-buten-1-ol(114716-44-8)

Safety Data

• Hazardous Substances Data: 114716-44-8(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 118574-32-6 2-<1-chloro-2-(E)-butenyl>-4,4,5,5-tetramethyl-1,3,2-dioxoborolane 
• 114716-34-6 2-<1-chloro-2-(Z)-butenyl>-4,4,5,5,-tetramethyl-1,3,2-dioxaborolane 
• 51157-81-4 1,1-dichloro-but-2-ene 

Downstream Products

• 79139-02-9 (1R*,2R*,3Z)-2-methyl-1-phenyl-4-trimethylsilyl-3-buten-1-ol 
• 114653-25-7 Isopropyl-carbamic acid (Z)-(1R,2R)-4-chloro-2-methyl-1-phenyl-but-3-enyl ester 
• 114653-26-8 Isopropyl-carbamic acid (Z)-(1S,2S)-4-chloro-2-methyl-1-phenyl-but-3-enyl ester 

Relevant articles and documents

Chemo- and Stereoselective Crotylation of Aldehydes and Cyclic Aldimines with Allylic gem-Diboronate Ester

We report a highly chemo- and stereoselective crotylation of aldehydes and cyclic aldimines with allylic-gem-diboronate ester as a new type of organoboron reagent. The allylic-gem-diboronate ester undergoes the crotylation with aldehydes and cyclic aldimines in excellent stereoselectivity, forming anti-5,6-disubstituted oxaborinin-2-ols or (E)-δ-boryl-anti-homoallylic amines in high efficiency. The reaction shows a wide range of substrate scope and excellent functional group tolerance. The synthetic applications of the obtained products, including stereospecific C-C, C-O, and C-Cl bond formation, are also demonstrated.

Stereoselective Synthesis of Alcohols, XXVII Addition of (α-Chlorocrotyl)boronates to Aldehydes

(Z)-(α-Chlorocrotyl)boronates 3 add to nonchiral aldehydes to give homoallyl alcohols 5 with a syn-β-positioned methyl group and an (E)-chloroalkenyl unit.The diastereoselectivity in fafour of 5 is around 90percent.The corresponding (E)-(α-chlorocrotyl)bo