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(3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol is a complex organic compound characterized by its molecular structure that includes tetrahydrofuran and dioxol rings. It is a derivative of 2,2-dimethyl-1,3-dioxolane, featuring a tert-butyldiphenylsilyl group attached to the oxygen atom. (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol is known for its unique structural properties and plays a significant role in various chemical processes.

114738-04-4

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  • (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol

    Cas No: 114738-04-4

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  • (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol

    Cas No: 114738-04-4

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  • (3AS,5R,6R,6AS)-5-(((TERT-BUTYLDIPHENYLSILYL)OXY)METHYL)-2,2-DIMETHYLTETRAHYDROFURO[2,3-D][1,3]DIOXOL-6-OL

    Cas No: 114738-04-4

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114738-04-4 Usage

Uses

Used in Pharmaceutical and Biotechnology Industries:
(3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol serves as a protecting group in organic synthesis, which is crucial for preventing unwanted reactions from occurring in specific parts of a molecule. This function is particularly valuable in the pharmaceutical and biotechnology sectors, where the synthesis of complex organic molecules is a common practice.
Used in Organic Synthesis:
In the realm of organic synthesis, (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol is utilized as a strategic component to control the reactivity of certain molecular sites. This selective protection allows chemists to carry out reactions on specific parts of a molecule without affecting others, thereby facilitating the synthesis of intricate organic compounds with precision and efficiency.
Used in Chemical Reactions and Processes:
Owing to its distinctive structure and properties, (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol finds applications in a variety of chemical reactions and processes. Its versatility and stability make it a valuable asset in the development and execution of advanced chemical procedures, contributing to the advancement of the field.

Check Digit Verification of cas no

The CAS Registry Mumber 114738-04-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,7,3 and 8 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 114738-04:
(8*1)+(7*1)+(6*4)+(5*7)+(4*3)+(3*8)+(2*0)+(1*4)=114
114 % 10 = 4
So 114738-04-4 is a valid CAS Registry Number.

114738-04-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol

1.2 Other means of identification

Product number -
Other names 5-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-β-D-arabinofuranose

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:114738-04-4 SDS

114738-04-4Relevant articles and documents

The Miharamycins and Amipurimycin: their Structural Revision and the Total Synthesis of the Latter

Wang, Shengyang,Zhang, Qingju,Zhao, Yachen,Sun, Jiansong,Kang, Wenjia,Wang, Fei,Pan, Haixue,Tang, Gongli,Yu, Biao

, p. 10558 - 10562 (2019)

The structural puzzle of amipurimycin, a peptidyl nucleoside antibiotic, is solved by total synthesis and X-ray diffraction analysis, with the originally proposed configurations at C3′ and C8′ inverted and those at C6′, C2′′, and C3′′ corrected. A similar structural revision of the relevant miharamycins is proposed via chemical transformations and then validated by X-ray diffraction analysis. The miharamycins bear an unusual trans-fused dioxabicyclo[4.3.0]nonane sugar scaffold, which was previously assigned as being in the cis configuration.

Elongation of the side chain by linear alkyl groups increases the potency of salacinol, a potent α-glucosidase inhibitor from the Ayurvedic traditional medicine “Salacia,” against human intestinal maltase

Takashima, Katsuki,Sakano, Mika,Kinouchi, Eri,Nakamura, Shinya,Marumoto, Shinsuke,Ishikawa, Fumihiro,Ninomiya, Kiyofumi,Nakanishi, Isao,Morikawa, Toshio,Tanabe, Genzoh

, (2021)

Four chain-extended analogs (12a–12d) and two related de-O-sulfonated analogs (13a and 13c) by introducing alkyl groups (a: R = C3H7, b R = C6H13, c: R = C8H17, d: R = C10H2

CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF

-

, (2021/11/05)

Provided are a compound of formula (I), an optical isomer thereof, a pharmaceutically acceptable salt thereof, uses of said compound acting as a STING agonist.

CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS

-

, (2019/02/13)

The present invention is directed to compounds of the formulae I, II and III as shown below wherein all substituents are defined herein, as well as pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.

NOVEL 3-SUBSTITUTED 5-AMINO-6H-THIAZOLO[4,5-D]PYRIMIDINE-2,7-DIONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION

-

, (2016/08/07)

The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF

-

, (2016/03/08)

Disclosed herein are nucleosides, nucleotides and nucleotide analogs, methods of synthesizing the same and methods of treating diseases and/or conditions such as a Coronaviridae virus, a Togaviridae virus, a Hepeviridae virus and/or a Bunyaviridae virus infection with one or more nucleosides, nucleotides and nucleotide analogs.

NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND USES RELATED THERETO

-

, (2015/03/28)

This disclosure relates to nucleotide and nucleoside therapeutic compositions and uses in treating infectious diseases, viral infections, and cancer, where the base of the nucleotide or nucleoside contains at least one thiol, thione or thioether.

Synthesis and biological evaluation of arabinose 5-phosphate mimics modified at position five

Cipolla, Laura,Airoldi, Cristina,Sperandeo, Paola,Gianera, Serena,Polissi, Alessandra,Nicotra, Francesco,Gabrielli, Luca

, p. 186 - 191 (2014/05/20)

A set of new metabolically stable arabinose 5-phosphate analogues possessing phosphate mimetic groups at position 5 was synthesised. Their ability to interact with arabinose 5-phosphate isomerase from Pseudomonas aeruginosa was evaluated by STD-NMR studie

Phosphonate analogues of arabinose 5-phosphate: Putative ligands for arabinose 5-phosphate isomerases

Gabrielli, Luca,Airoldi, Cristina,Sperandeo, Paola,Gianera, Serena,Polissi, Alessandra,Nicotra, Francesco,Cipolla, Laura

, p. 7776 - 7784 (2013/12/04)

Metabolically stable arabinose 5-phosphate analogues possessing phosphate mimetic groups at the 5-position were synthesized and evaluated by saturation-transfer-difference (STD) NMR studies for their ability to interact with arabinose 5-phosphate isomeras

A POSITRON EMISSION TOMOGRAPHY PROBE TO MONITOR SELECTED SUGAR METABOLISM IN VIVO

-

Page/Page column 24, (2013/12/03)

The invention disclosed herein discloses selected ribose isomers that are useful as PET probes (e.g. [18F]-2-fluoro-2-deoxy-arabinose). These PET probes are useful, for example, in methods designed to monitor physiological processes including ribose metab

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