114738-04-4

Basic information

• Product Name: (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol
• Synonyms: (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol
• CAS NO: 114738-04-4
• Molecular Formula: C₂₄H₃₂O₅Si
• Molecular Weight: 428.59338
• EINECS: -0
• Mol File: 114738-04-4.mol
• Article Data: 20

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol(114738-04-4)
• EPA Substance Registry System: (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol(114738-04-4)

Safety Data

• Hazardous Substances Data: 114738-04-4(Hazardous Substances Data)

Usage

General Description

The chemical "(3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol" is a complex compound with a molecular structure containing tetrahydrofuran and dioxol rings. It is a derivative of 2,2-dimethyl-1,3-dioxolane, and it has a tert-butyldiphenylsilyl group attached to the oxygen atom. (3aS,5R,6R,6aS)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol is used as a protecting group in organic synthesis to prevent unwanted reactions from occurring in specific parts of a molecule. It is commonly used in the pharmaceutical and biotechnology industries for the synthesis of complex organic molecules. Due to its unique structure and properties, it has applications in various chemical reactions and processes.

Upstream product

• 168608-39-7 (3S,4S,5R)-5-(((tert-butyldiphenylsilyl)oxy)methyl)tetrahydrofuran-2,3,4-triol 
• 77-76-9 2,2-dimethoxy-propane 
• 67-64-1 acetone 
• 608-45-7 α-D-arabinopyranose 
• 532-20-7 D-arabinofuranose 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 10323-20-3 D-Arabinose 
• 28697-53-2 D-arabinopyranose 
• 1941-50-0 D-arabinose diethyl dithioacetal 
• 162517-90-0 5-O-(tert-butyldiphenylsilyl)-D-arabinose diethyldithioacetal 

Downstream Products

• 168103-00-2 (((3aS,5R,6R,6aS)-6-(benzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methoxy)(tert-butyl)diphenylsilane 
• 1294500-45-0 5-azido-3-O-benzyl-1,2-O-isopropylidene-β-D-arabinofuranose 
• 1294500-46-1 5-azido-3-O-benzyl-5-deoxy-D-arabinono-1,4-lactone 
• 40429-53-6 5-O-p-toluenesulfonyl-3-O-benzyl-1,2-O-isopropylidene-β-D-arabinofuranose 
• 1220093-28-6 3-deoxy-1,2-O-isopropylidene-β-D-threo-pentofuranose 5-diphenylphosphate 
• 168969-77-5 [(3aS,5S,6aS)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methoxy-tert-butyl-diphenyl-silane 
• 1220093-26-4 5-O-t-butyldiphenylsilyl-3-O-(imidazolylthiocarbonyl)-1,2-O-isopropylidene-β-D-threo-pentofuranose 
• 213313-43-0 methyl 3,5-di-O-benzyl-D-arabinofuranoside 
• 191543-71-2 methyl 3,5-di-O-benzyl-α-D-ribofuranoside 
• 817204-28-7 C₂₀H₂₂O₅ 

Relevant articles and documents

The Miharamycins and Amipurimycin: their Structural Revision and the Total Synthesis of the Latter

The structural puzzle of amipurimycin, a peptidyl nucleoside antibiotic, is solved by total synthesis and X-ray diffraction analysis, with the originally proposed configurations at C3′ and C8′ inverted and those at C6′, C2′′, and C3′′ corrected. A similar structural revision of the relevant miharamycins is proposed via chemical transformations and then validated by X-ray diffraction analysis. The miharamycins bear an unusual trans-fused dioxabicyclo[4.3.0]nonane sugar scaffold, which was previously assigned as being in the cis configuration.

CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF

Provided are a compound of formula (I), an optical isomer thereof, a pharmaceutically acceptable salt thereof, uses of said compound acting as a STING agonist.

NOVEL 3-SUBSTITUTED 5-AMINO-6H-THIAZOLO[4,5-D]PYRIMIDINE-2,7-DIONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION

The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.